Tapentadol Hydrochloride
8 NDCs across 1 manufacturer|0 Generic,8 Brand
Tapentadol Hydrochloride is used to treat pain, per the National Library of Medicine's MED-RT classification.
▸ More about this market▾ Less
The brand product was first FDA-approved on Nov 20, 2008, and the first generic was approved Jan 26, 2026. FDA's Orange Book lists 9 AB-rated (therapeutically equivalent) products for this ingredient.
Tapentadol Hydrochloride is available as 8 NDCs from 1 manufacturer (0 generic, 8 brand), with NADAC prices from $10.15 to $40.19 per EA — the most expensive product costs about 4.0× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
8
0G / 8B
Manufacturers
1
competing in market
Price Spread
$10.15 – $40.19
per EA
7d Activity
avg +0.0% WoW · of 8 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Explore this market from other angles
Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Collegium Pharmaceutical, Inc. manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Opioid Agonist class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
Move from this single molecule into the current cross-market mover and volatility view.
Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
1 manufacturer producing TAPENTADOL HYDROCHLORIDE
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
NUCYNTA ER 250 MG TABLET | $40.1901 per EA | — |
NUCYNTA ER 200 MG TABLET | $32.1599 per EA | — |
NUCYNTA ER 150 MG TABLET | $25.3560 per EA | — |
NUCYNTA ER 100 MG TABLET | $19.6279 per EA | — |
NUCYNTA 100 MG TABLET | $15.7978 per EA | — |
NUCYNTA 75 MG TABLET | $11.8592 per EA | — |
NUCYNTA ER 50 MG TABLET | $10.6278 per EA | — |
NUCYNTA 50 MG TABLET | $10.1486 per EA | — |
Frequently Asked Questions
What is Tapentadol Hydrochloride used to treat?
Tapentadol Hydrochloride is used to treat pain, per the National Library of Medicine's MED-RT classification.
When did Tapentadol Hydrochloride become available as a generic?
FDA approved the first generic Tapentadol Hydrochloride (ANDA) on Jan 26, 2026. The Orange Book currently lists 9 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How many Tapentadol Hydrochloride products are on the market?
The Tapentadol Hydrochloride drug market contains 8 NDCs from 1 manufacturer — 0 generic and 8 brand products.
What is the price range for Tapentadol Hydrochloride?
NADAC reference prices for Tapentadol Hydrochloride range from $10.1486 to $40.1901 per EA — the most expensive product costs about 4.0× the cheapest.
Which manufacturers make Tapentadol Hydrochloride?
1 manufacturer lists Tapentadol Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Collegium Pharmaceutical, Inc. (8).