Tapentadol Hydrochloride
8 NDCs across 1 manufacturer|0 Generic,8 Brand
Tapentadol Hydrochloride is used to treat pain, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Nov 20, 2008, and the first generic was approved Jan 26, 2026. FDA's Orange Book lists 6 AB-rated (therapeutically equivalent) products for this ingredient.
Tapentadol Hydrochloride is available as 8 NDCs from 1 manufacturer (0 generic, 8 brand), with NADAC prices from $10.15 to $40.19 per EA — the most expensive product costs about 4.0× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
8
0G / 8B
Manufacturers
1
competing in market
Price Spread
$10.15 – $40.19
per EA
7d Activity
avg +0.0% WoW · of 8 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
1 manufacturer producing TAPENTADOL HYDROCHLORIDE
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
NUCYNTA ER 250 MG TABLET | $40.1901 per EA | — |
NUCYNTA ER 200 MG TABLET | $32.1599 per EA | — |
NUCYNTA ER 150 MG TABLET | $25.3560 per EA | — |
NUCYNTA ER 100 MG TABLET | $19.6279 per EA | — |
NUCYNTA 100 MG TABLET | $15.7978 per EA | — |
NUCYNTA 75 MG TABLET | $11.8592 per EA | — |
NUCYNTA ER 50 MG TABLET | $10.6278 per EA | — |
NUCYNTA 50 MG TABLET | $10.1486 per EA | — |
Frequently Asked Questions
What is Tapentadol Hydrochloride used to treat?
Tapentadol Hydrochloride is used to treat pain, per the National Library of Medicine's MED-RT classification.
When did Tapentadol Hydrochloride become available as a generic?
FDA approved the first generic Tapentadol Hydrochloride (ANDA) on Jan 26, 2026. The Orange Book currently lists 6 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How many Tapentadol Hydrochloride products are on the market?
The Tapentadol Hydrochloride drug market contains 8 NDCs from 1 manufacturer — 0 generic and 8 brand products.
What is the price range for Tapentadol Hydrochloride?
NADAC reference prices for Tapentadol Hydrochloride range from $10.1486 to $40.1901 per EA — the most expensive product costs about 4.0× the cheapest.
Which manufacturers make Tapentadol Hydrochloride?
1 manufacturer lists Tapentadol Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Collegium Pharmaceutical, Inc. (8).