Product Information
ORENCIA 125 MG/ML SYRINGE is a brand product labeled by E.R. Squibb & Sons, L.L.C., priced at $1469.2280 per ML under NDC 00003218811. Its NADAC has been published 651 times since Apr 16, 2014.
Strength
125 mg/mL
Manufacturer
E.R. Squibb & Sons, L.L.C.NDC
00003218811
Classification
Brand
Dosage Form
INJECTION, SOLUTION
Route
SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
ABATACEPTApproval Type
Biologic (BLA)
FDA Application
BLA125118On Market Since
7/29/2011
Pharmacological Classes
Price Statistics
The NADAC for ORENCIA 125 MG/ML SYRINGE has been published 651 times since Apr 16, 2014, and over the history we have for it it has risen 157.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1469.2280 per ML |
|---|---|
| All-time high | $1472.4470 (May 13, 2026) |
| All-time low | $571.6804 (Apr 16, 2014) |
| 52-week high | $1472.4470 |
| 52-week low | $1440.7363 |
| Median price | $1126.7123 |
| Average price | $1106.7438 |
| Largest weekly change | +9.9% (Jun 10, 2015) |
| Weeks tracked | 651 |
| Tracking since | Apr 16, 2014 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
E.R. Squibb & Sons, L.L.C. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
abatacept market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ORENCIA 125 MG/ML SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for ORENCIA 125 MG/ML SYRINGE, manufactured by E.R. Squibb & Sons, L.L.C., is $1469.2280 per ML (NDC 00003218811), effective Sep 30, 2026.
How has the price of ORENCIA 125 MG/ML SYRINGE changed over time?
Over the history we have for it, the NADAC for ORENCIA 125 MG/ML SYRINGE has risen 157.0%. It has been tracked across 651 weekly CMS publications since Apr 16, 2014.
What are the highest and lowest recorded NADAC prices for ORENCIA 125 MG/ML SYRINGE?
Since Apr 16, 2014, the NADAC for ORENCIA 125 MG/ML SYRINGE has ranged from a low of $571.6804 (Apr 16, 2014) to a high of $1472.4470 (May 13, 2026), with a median of $1126.7123 per ML.
Are there cheaper alternatives to ORENCIA 125 MG/ML SYRINGE?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ORENCIA 125 MG/ML SYRINGE in a comparable dosage form, but none are currently priced below it.
Who manufactures ORENCIA 125 MG/ML SYRINGE?
ORENCIA 125 MG/ML SYRINGE (NDC 00003218811) is labeled by E.R. Squibb & Sons, L.L.C., and CMS classifies it as a brand product.