Product Information

EMEND 125 MG POWDER PACKET is a brand product labeled by Merck Sharp & Dohme LLC, priced at $327.3840 per EA under NDC 00006306603. Its NADAC has been published 110 times since Jul 17, 2024.

FDA first approved this application on Dec 17, 2015.

The High Outlier badge above means this manufacturer's average price in the aprepitant market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

EMEND 125 MG POWDER PACKET

aprepitant
$327.3840per EA
High Outlier

Strength

125 mg/1

NDC

00006306603

Classification

Brand

Dosage Form

POWDER, FOR SUSPENSION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

APREPITANT

Approval Type

New Drug (NDA)

FDA Application

NDA207865

FDA Approved

12/17/2015

On Market Since

12/17/2015

Pharmacological Classes

Cytochrome P450 2C9 Inducers
Cytochrome P450 3A4 Inducers
Cytochrome P450 3A4 Inhibitors
Neurokinin 1 Antagonists
Substance P/Neurokinin-1 Receptor Antagonist

Price Statistics

The NADAC for EMEND 125 MG POWDER PACKET has been published 110 times since Jul 17, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$327.3840 per EA
All-time high$327.8980 (Aug 12, 2026)
All-time low$324.0400 (Jul 23, 2025)
52-week high$327.8980
52-week low$325.1171
Median price$325.3075
Average price$325.6771
Largest weekly change+0.6% (May 20, 2026)
Weeks tracked110
Tracking sinceJul 17, 2024

Price History

1W

-0.2%

1M

-0.2%

3M

-0.2%

6M

+0.4%

1Y

+0.7%

3Y

N/A

5Y

N/A

All

+0.7%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the aprepitant market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of EMEND 125 MG POWDER PACKET?

The current National Average Drug Acquisition Cost (NADAC) for EMEND 125 MG POWDER PACKET, manufactured by Merck Sharp & Dohme LLC, is $327.3840 per EA (NDC 00006306603), effective Aug 19, 2026.

How has the price of EMEND 125 MG POWDER PACKET changed over time?

Over the history we have for it, the NADAC for EMEND 125 MG POWDER PACKET has held within roughly two percent of its current level. It has been tracked across 110 weekly CMS publications since Jul 17, 2024.

What are the highest and lowest recorded NADAC prices for EMEND 125 MG POWDER PACKET?

Since Jul 17, 2024, the NADAC for EMEND 125 MG POWDER PACKET has ranged from a low of $324.0400 (Jul 23, 2025) to a high of $327.8980 (Aug 12, 2026), with a median of $325.3075 per EA.

Are there cheaper alternatives to EMEND 125 MG POWDER PACKET?

No other NADAC-published product currently shares the active ingredient and strength of EMEND 125 MG POWDER PACKET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures EMEND 125 MG POWDER PACKET?

EMEND 125 MG POWDER PACKET (NDC 00006306603) is labeled by Merck Sharp & Dohme LLC, and CMS classifies it as a brand product.