Product Information

EFFEXOR XR 150 MG CAPSULE is a brand product labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., priced at $21.6254 per EA under NDC 00008083621. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Oct 20, 1997. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the VENLAFAXINE HYDROCHLORIDE market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

EFFEXOR XR 150 MG CAPSULE

VENLAFAXINE HYDROCHLORIDE
$21.6254per EA
Discontinued
High Outlier

Strength

150 mg/1

NDC

00008083621

Classification

Brand

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

VENLAFAXINE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA020699

FDA Approved

10/20/1997

TE Code

AB

On Market Since

11/1/1997

Pharmacological Classes

Norepinephrine Uptake Inhibitors
Serotonin Uptake Inhibitors
Serotonin and Norepinephrine Reuptake Inhibitor

Price Statistics

The NADAC for EFFEXOR XR 150 MG CAPSULE has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 223.4%. The table below summarizes its recorded NADAC range and movement.

Current price$21.6254 per EA
All-time high$21.6254 (Aug 19, 2026)
All-time low$6.6869 (Nov 28, 2013)
52-week high$21.6254
52-week low$20.5777
Median price$16.1750
Average price$15.3659
Largest weekly change+9.4% (Jun 8, 2016)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+0.0%

1M

+0.0%

3M

+0.1%

6M

+0.1%

1Y

+4.8%

3Y

+13.4%

5Y

+27.3%

All

+223.4%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of EFFEXOR XR 150 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for EFFEXOR XR 150 MG CAPSULE, manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., is $21.6254 per EA (NDC 00008083621), effective Aug 19, 2026.

How has the price of EFFEXOR XR 150 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for EFFEXOR XR 150 MG CAPSULE has risen 223.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for EFFEXOR XR 150 MG CAPSULE?

Since Nov 28, 2013, the NADAC for EFFEXOR XR 150 MG CAPSULE has ranged from a low of $6.6869 (Nov 28, 2013) to a high of $21.6254 (Aug 19, 2026), with a median of $16.1750 per EA.

Are there cheaper alternatives to EFFEXOR XR 150 MG CAPSULE?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, VENLAFAXINE HCL ER 150 MG CAP, is $0.1162 per EA — about 99% below EFFEXOR XR 150 MG CAPSULE.

Who manufactures EFFEXOR XR 150 MG CAPSULE?

EFFEXOR XR 150 MG CAPSULE (NDC 00008083621) is labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., and CMS classifies it as a brand product.