Product Information

XANAX 0.25 MG TABLET is a brand product labeled by Pharmacia & Upjohn Company LLC, priced at $5.6318 per EA under NDC 00009002901. Its NADAC has been published 621 times since Nov 28, 2013.

FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the alprazolam market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

XANAX 0.25 MG TABLET

alprazolam
$5.6318per EA
High Outlier
DEA Schedule CIV

Strength

.25 mg/1

NDC

00009002901

Classification

Brand

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ALPRAZOLAM

Approval Type

New Drug (NDA)

FDA Application

NDA018276

FDA Approved

Before 1982

TE Code

AB

On Market Since

10/16/1981

Pharmacological Classes

Benzodiazepine
Benzodiazepines

Price Statistics

The NADAC for XANAX 0.25 MG TABLET has been published 621 times since Nov 28, 2013, and over the history we have for it it has risen 225.8%. The table below summarizes its recorded NADAC range and movement.

Current price$5.6318 per EA
All-time high$5.6478 (May 13, 2026)
All-time low$1.7286 (Nov 28, 2013)
52-week high$5.6478
52-week low$5.3751
Median price$4.0429
Average price$3.9451
Largest weekly change+12.0% (Jan 6, 2016)
Weeks tracked621
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

0.0%

3M

+0.1%

6M

-0.3%

1Y

+4.6%

3Y

+12.7%

5Y

+26.6%

All

+225.8%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of XANAX 0.25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for XANAX 0.25 MG TABLET, manufactured by Pharmacia & Upjohn Company LLC, is $5.6318 per EA (NDC 00009002901), effective Aug 19, 2026.

How has the price of XANAX 0.25 MG TABLET changed over time?

Over the history we have for it, the NADAC for XANAX 0.25 MG TABLET has risen 225.8%. It has been tracked across 621 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for XANAX 0.25 MG TABLET?

Since Nov 28, 2013, the NADAC for XANAX 0.25 MG TABLET has ranged from a low of $1.7286 (Nov 28, 2013) to a high of $5.6478 (May 13, 2026), with a median of $4.0429 per EA.

Are there cheaper alternatives to XANAX 0.25 MG TABLET?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALPRAZOLAM 0.25 MG TABLET, is $0.0239 per EA — about 99% below XANAX 0.25 MG TABLET.

Who manufactures XANAX 0.25 MG TABLET?

XANAX 0.25 MG TABLET (NDC 00009002901) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand product.