Product Information

RESTASIS MULTIDOSE 0.05% EYE is a brand product labeled by Allergan, Inc., priced at $112.3176 per ML under NDC 00023530105. Its NADAC has been published 484 times since May 17, 2017.

FDA first approved this application on Dec 23, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the cyclosporine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

RESTASIS MULTIDOSE 0.05% EYE

cyclosporine
$112.3176per ML
High Outlier

Strength

.5 mg/mL

Manufacturer

Allergan, Inc.

NDC

00023530105

Classification

Brand

Dosage Form

EMULSION

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

CYCLOSPORINE

Approval Type

New Drug (NDA)

FDA Application

NDA050790

FDA Approved

12/23/2002

TE Code

AB

On Market Since

11/10/2016

Pharmacological Classes

Calcineurin Inhibitor Immunosuppressant
Calcineurin Inhibitors
Cytochrome P450 3A4 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for RESTASIS MULTIDOSE 0.05% EYE has been published 484 times since May 17, 2017, and over the history we have for it it has risen 39.6%. The table below summarizes its recorded NADAC range and movement.

Current price$112.3176 per ML
All-time high$112.6932 (Oct 12, 2022)
All-time low$80.4772 (May 17, 2017)
52-week high$112.4633
52-week low$112.3161
Median price$107.3279
Average price$104.2725
Largest weekly change+9.5% (Jan 9, 2019)
Weeks tracked484
Tracking sinceMay 17, 2017

Price History

1W

-0.0%

1M

-0.0%

3M

-0.0%

6M

-0.0%

1Y

-0.1%

3Y

-0.1%

5Y

+4.7%

All

+39.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the cyclosporine market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of RESTASIS MULTIDOSE 0.05% EYE?

The current National Average Drug Acquisition Cost (NADAC) for RESTASIS MULTIDOSE 0.05% EYE, manufactured by Allergan, Inc., is $112.3176 per ML (NDC 00023530105), effective Aug 19, 2026.

How has the price of RESTASIS MULTIDOSE 0.05% EYE changed over time?

Over the history we have for it, the NADAC for RESTASIS MULTIDOSE 0.05% EYE has risen 39.6%. It has been tracked across 484 weekly CMS publications since May 17, 2017.

What are the highest and lowest recorded NADAC prices for RESTASIS MULTIDOSE 0.05% EYE?

Since May 17, 2017, the NADAC for RESTASIS MULTIDOSE 0.05% EYE has ranged from a low of $80.4772 (May 17, 2017) to a high of $112.6932 (Oct 12, 2022), with a median of $107.3279 per ML.

Are there cheaper alternatives to RESTASIS MULTIDOSE 0.05% EYE?

No other NADAC-published product currently shares the active ingredient and strength of RESTASIS MULTIDOSE 0.05% EYE in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures RESTASIS MULTIDOSE 0.05% EYE?

RESTASIS MULTIDOSE 0.05% EYE (NDC 00023530105) is labeled by Allergan, Inc., and CMS classifies it as a brand product.