Product Information

DEPAKOTE ER 500 MG TABLET is a brand product labeled by AbbVie Inc., priced at $6.5027 per EA under NDC 00074740213. Its NADAC has been published 212 times since Jun 8, 2022.

The High Outlier badge above means this manufacturer's average price in the Divalproex Sodium market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

DEPAKOTE ER 500 MG TABLET

Divalproex Sodium
$6.5027per EA
High Outlier

Strength

500 mg/1

Manufacturer

AbbVie Inc.

NDC

00074740213

Classification

Brand

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

DIVALPROEX SODIUM

Approval Type

New Drug (NDA)

FDA Application

NDA021168

On Market Since

8/4/2000

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Mood Stabilizer

Price Statistics

The NADAC for DEPAKOTE ER 500 MG TABLET has been published 212 times since Jun 8, 2022, and over the history we have for it it has risen 21.8%. The table below summarizes its recorded NADAC range and movement.

Current price$6.5027 per EA
All-time high$6.5073 (Jun 10, 2026)
All-time low$5.3376 (Jun 8, 2022)
52-week high$6.5073
52-week low$6.1904
Median price$5.9041
Average price$5.8939
Largest weekly change+5.0% (Jan 10, 2024)
Weeks tracked212
Tracking sinceJun 8, 2022

Price History

1W

0.0%

1M

-0.1%

3M

+0.0%

6M

+5.0%

1Y

+5.0%

3Y

+15.6%

5Y

N/A

All

+21.8%

Generic Alternatives

The matcher finds 12 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DEPAKOTE ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DEPAKOTE ER 500 MG TABLET, manufactured by AbbVie Inc., is $6.5027 per EA (NDC 00074740213), effective Jun 24, 2026.

How has the price of DEPAKOTE ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for DEPAKOTE ER 500 MG TABLET has risen 21.8%. It has been tracked across 212 weekly CMS publications since Jun 8, 2022.

What are the highest and lowest recorded NADAC prices for DEPAKOTE ER 500 MG TABLET?

Since Jun 8, 2022, the NADAC for DEPAKOTE ER 500 MG TABLET has ranged from a low of $5.3376 (Jun 8, 2022) to a high of $6.5073 (Jun 10, 2026), with a median of $5.9041 per EA.

Are there cheaper alternatives to DEPAKOTE ER 500 MG TABLET?

Yes. 12 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, DIVALPROEX SOD DR 500 MG TAB, is $0.1228 per EA — about 98% below DEPAKOTE ER 500 MG TABLET.

Who manufactures DEPAKOTE ER 500 MG TABLET?

DEPAKOTE ER 500 MG TABLET (NDC 00074740213) is labeled by AbbVie Inc., and CMS classifies it as a brand product.