Product Information

FEMARA 2.5 MG TABLET is a brand product labeled by Novartis Pharmaceuticals Corporation, priced at $27.1160 per EA under NDC 00078024915. Its NADAC has been published 361 times since Nov 28, 2013.

FDA first approved this application on Jul 25, 1997. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the letrozole market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

FEMARA 2.5 MG TABLET

letrozole
$27.1160per EA
High Outlier

Strength

2.5 mg/1

NDC

00078024915

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

1/7/2026

Active Ingredients

LETROZOLE

Approval Type

New Drug (NDA)

FDA Application

NDA020726

FDA Approved

7/25/1997

TE Code

AB

On Market Since

7/31/1997

Pharmacological Classes

Aromatase Inhibitor
Aromatase Inhibitors

Price Statistics

The NADAC for FEMARA 2.5 MG TABLET has been published 361 times since Nov 28, 2013, and over the history we have for it it has risen 49.0%. The table below summarizes its recorded NADAC range and movement.

Current price$27.1160 per EA
All-time high$27.1160 (Aug 19, 2026)
All-time low$18.1938 (Nov 28, 2013)
52-week high$27.1160
52-week low$26.3262
Median price$22.6235
Average price$22.9888
Largest weekly change+13.3% (Sep 18, 2024)
Weeks tracked361
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+2.8%

3Y

+19.9%

5Y

+19.9%

All

+49.0%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 99%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of FEMARA 2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for FEMARA 2.5 MG TABLET, manufactured by Novartis Pharmaceuticals Corporation, is $27.1160 per EA (NDC 00078024915), effective Aug 19, 2026.

How has the price of FEMARA 2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for FEMARA 2.5 MG TABLET has risen 49.0%. It has been tracked across 361 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for FEMARA 2.5 MG TABLET?

Since Nov 28, 2013, the NADAC for FEMARA 2.5 MG TABLET has ranged from a low of $18.1938 (Nov 28, 2013) to a high of $27.1160 (Aug 19, 2026), with a median of $22.6235 per EA.

Are there cheaper alternatives to FEMARA 2.5 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LETROZOLE 2.5 MG TABLET, is $0.1511 per EA — about 99% below FEMARA 2.5 MG TABLET.

Who manufactures FEMARA 2.5 MG TABLET?

FEMARA 2.5 MG TABLET (NDC 00078024915) is labeled by Novartis Pharmaceuticals Corporation, and CMS classifies it as a brand product.