Product Information
AMANTADINE 50 MG/5 ML SOLUTION is a generic product labeled by PAI Holdings LLC, priced at $0.0498 per ML under NDC 00121064616. Its NADAC has been published 653 times since Nov 28, 2013.
FDA first approved this application on Jul 17, 1995. Its Orange Book therapeutic-equivalence code is AA.
The Low Outlier badge above means this manufacturer's average price in the AMANTADINE HYDROCHLORIDE market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/5mL
Manufacturer
PAI Holdings LLCNDC
00121064616
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
AMANTADINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA074509FDA Approved
7/17/1995
TE Code
AA
On Market Since
7/17/1995
Pharmacological Classes
Price Statistics
The NADAC for AMANTADINE 50 MG/5 ML SOLUTION has been published 653 times since Nov 28, 2013, and over the history we have for it it has risen 69.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0498 per ML |
|---|---|
| All-time high | $0.0600 (Dec 11, 2024) |
| All-time low | $0.0165 (Nov 18, 2020) |
| 52-week high | $0.0509 |
| 52-week low | $0.0481 |
| Median price | $0.0228 |
| Average price | $0.0276 |
| Largest weekly change | +90.2% (Apr 17, 2024) |
| Weeks tracked | 653 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the AMANTADINE HYDROCHLORIDE market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
PAI Holdings LLC manufacturer profile
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Drug market
AMANTADINE HYDROCHLORIDE market comparison
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Therapeutic class
Influenza A M2 Protein Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of AMANTADINE 50 MG/5 ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for AMANTADINE 50 MG/5 ML SOLUTION, manufactured by PAI Holdings LLC, is $0.0498 per ML (NDC 00121064616), effective Sep 30, 2026.
How has the price of AMANTADINE 50 MG/5 ML SOLUTION changed over time?
Over the history we have for it, the NADAC for AMANTADINE 50 MG/5 ML SOLUTION has risen 69.3%. It has been tracked across 653 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for AMANTADINE 50 MG/5 ML SOLUTION?
Since Nov 28, 2013, the NADAC for AMANTADINE 50 MG/5 ML SOLUTION has ranged from a low of $0.0165 (Nov 18, 2020) to a high of $0.0600 (Dec 11, 2024), with a median of $0.0228 per ML.
Are there cheaper alternatives to AMANTADINE 50 MG/5 ML SOLUTION?
No other NADAC-published product currently shares the active ingredient and strength of AMANTADINE 50 MG/5 ML SOLUTION in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures AMANTADINE 50 MG/5 ML SOLUTION?
AMANTADINE 50 MG/5 ML SOLUTION (NDC 00121064616) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.