Historical record - last NADAC effective date: 6/19/2024

Product Information

PREDNISOLONE 20 MG/5 ML SOLN is a generic product labeled by PAI Holdings LLC, priced at $2.4495 per ML under NDC 00121077708. Its NADAC has been published 61 times since Apr 17, 2024.

FDA first approved this application on Jun 9, 2008. Its Orange Book therapeutic-equivalence code is AA.

PREDNISOLONE 20 MG/5 ML SOLN

Prednisolone Sodium Phosphate
$2.4495per ML

Strength

20 mg/5mL

Manufacturer

PAI Holdings LLC

NDC

00121077708

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

6/19/2024

Approval Type

Generic (ANDA)

FDA Application

ANDA078988

FDA Approved

6/9/2008

TE Code

AA

On Market Since

1/31/2017

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for PREDNISOLONE 20 MG/5 ML SOLN has been published 61 times since Apr 17, 2024, and over the history we have for it it has declined 15.8%. The table below summarizes its recorded NADAC range and movement.

Current price$2.4495 per ML
All-time high$2.9108 (May 15, 2024)
All-time low$2.4495 (May 22, 2024)
Median price$2.4495
Average price$2.4874
Largest weekly change-15.8% (May 22, 2024)
Weeks tracked61
Tracking sinceApr 17, 2024

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

-15.8%

Last surveyed Jun 11, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PREDNISOLONE 20 MG/5 ML SOLN?

The current National Average Drug Acquisition Cost (NADAC) for PREDNISOLONE 20 MG/5 ML SOLN, manufactured by PAI Holdings LLC, is $2.4495 per ML (NDC 00121077708), effective Jun 11, 2025.

How has the price of PREDNISOLONE 20 MG/5 ML SOLN changed over time?

Over the history we have for it, the NADAC for PREDNISOLONE 20 MG/5 ML SOLN has declined 15.8%. It has been tracked across 61 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for PREDNISOLONE 20 MG/5 ML SOLN?

Since Apr 17, 2024, the NADAC for PREDNISOLONE 20 MG/5 ML SOLN has ranged from a low of $2.4495 (May 22, 2024) to a high of $2.9108 (May 15, 2024), with a median of $2.4495 per ML.

Are there cheaper alternatives to PREDNISOLONE 20 MG/5 ML SOLN?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PREDNISOLONE 20 MG/5 ML SOLN in a comparable dosage form, but none are currently priced below it.

Who manufactures PREDNISOLONE 20 MG/5 ML SOLN?

PREDNISOLONE 20 MG/5 ML SOLN (NDC 00121077708) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.