Product Information
ADVAIR 250-50 DISKUS is a brand product labeled by GlaxoSmithKline LLC, priced at $3.1083 per EA under NDC 00173069604. Its NADAC has been published 352 times since Nov 28, 2013.
FDA first approved this application on Aug 24, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
250; 50 ug/1; ug/1
Manufacturer
GlaxoSmithKline LLCNDC
00173069604
Classification
Brand
Dosage Form
POWDER
Route
RESPIRATORY (INHALATION)
Effective Date
11/20/2024
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
New Drug (NDA)
FDA Application
NDA021077FDA Approved
8/24/2000
TE Code
AB
On Market Since
2/5/2001
Pharmacological Classes
Price Statistics
The NADAC for ADVAIR 250-50 DISKUS has been published 352 times since Nov 28, 2013, and over the history we have for it it has declined 56.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.1083 per EA |
|---|---|
| All-time high | $10.4210 (Jan 16, 2019) |
| All-time low | $3.0947 (Apr 17, 2024) |
| 52-week high | $3.1083 |
| 52-week low | $3.1083 |
| Median price | $8.1965 |
| Average price | $7.4926 |
| Largest weekly change | -70.3% (Apr 17, 2024) |
| Weeks tracked | 352 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
-70.2%
5Y
-70.2%
All
-56.1%
Last surveyed Nov 12, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 59% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ADVAIR 250-50 DISKUS?
The current National Average Drug Acquisition Cost (NADAC) for ADVAIR 250-50 DISKUS, manufactured by GlaxoSmithKline LLC, is $3.1083 per EA (NDC 00173069604), effective Nov 12, 2025.
How has the price of ADVAIR 250-50 DISKUS changed over time?
Over the history we have for it, the NADAC for ADVAIR 250-50 DISKUS has declined 56.1%. It has been tracked across 352 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ADVAIR 250-50 DISKUS?
Since Nov 28, 2013, the NADAC for ADVAIR 250-50 DISKUS has ranged from a low of $3.0947 (Apr 17, 2024) to a high of $10.4210 (Jan 16, 2019), with a median of $8.1965 per EA.
Are there cheaper alternatives to ADVAIR 250-50 DISKUS?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FLUTICASONE-SALMETEROL 250-50, is $1.2785 per EA — about 59% below ADVAIR 250-50 DISKUS.
Who manufactures ADVAIR 250-50 DISKUS?
ADVAIR 250-50 DISKUS (NDC 00173069604) is labeled by GlaxoSmithKline LLC, and CMS classifies it as a brand product.