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Product Information

APLENZIN ER 522 MG TABLET is a brand product labeled by Bausch Health US LLC, priced at $212.4769 per EA under NDC 00187581230. Its NADAC has been published 512 times since Feb 11, 2015.

FDA first approved this application on Apr 23, 2008.

APLENZIN ER 522 MG TABLET

bupropion hydrobromide
$212.4769per EA

Strength

522 mg/1

NDC

00187581230

Classification

Brand

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

9/17/2025

Active Ingredients

BUPROPION HYDROBROMIDE

Approval Type

New Drug (NDA)

FDA Application

NDA022108

FDA Approved

4/23/2008

On Market Since

4/23/2008

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for APLENZIN ER 522 MG TABLET has been published 512 times since Feb 11, 2015, and over the history we have for it it has risen 295.1%. The table below summarizes its recorded NADAC range and movement.

Current price$212.4769 per EA
All-time high$213.6255 (May 14, 2025)
All-time low$53.7762 (Feb 11, 2015)
52-week high$212.4769
52-week low$212.1319
Median price$142.6286
Average price$148.9563
Largest weekly change+96.7% (Feb 17, 2016)
Weeks tracked512
Tracking sinceFeb 11, 2015

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

+0.2%

3Y

+20.1%

5Y

+37.7%

All

+295.1%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the bupropion hydrobromide market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of APLENZIN ER 522 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for APLENZIN ER 522 MG TABLET, manufactured by Bausch Health US LLC, is $212.4769 per EA (NDC 00187581230), effective Oct 1, 2025.

How has the price of APLENZIN ER 522 MG TABLET changed over time?

Over the history we have for it, the NADAC for APLENZIN ER 522 MG TABLET has risen 295.1%. It has been tracked across 512 weekly CMS publications since Feb 11, 2015.

What are the highest and lowest recorded NADAC prices for APLENZIN ER 522 MG TABLET?

Since Feb 11, 2015, the NADAC for APLENZIN ER 522 MG TABLET has ranged from a low of $53.7762 (Feb 11, 2015) to a high of $213.6255 (May 14, 2025), with a median of $142.6286 per EA.

Are there cheaper alternatives to APLENZIN ER 522 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of APLENZIN ER 522 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures APLENZIN ER 522 MG TABLET?

APLENZIN ER 522 MG TABLET (NDC 00187581230) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.