Product Information
ALPRAZOLAM ODT 0.25 MG TAB is a generic product labeled by Actavis Pharma, Inc., priced at $0.9697 per EA under NDC 00228401911. Its NADAC has been published 329 times since Nov 28, 2013.
FDA first approved this application on Mar 16, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00228401911
Classification
Generic
Dosage Form
TABLET, ORALLY DISINTEGRATING
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ALPRAZOLAMApproval Type
Generic (ANDA)
FDA Application
ANDA078561FDA Approved
3/16/2010
TE Code
AB
On Market Since
3/17/2010
Pharmacological Classes
Price Statistics
The NADAC for ALPRAZOLAM ODT 0.25 MG TAB has been published 329 times since Nov 28, 2013, and over the history we have for it it has declined 10.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9697 per EA |
|---|---|
| All-time high | $1.1305 (Nov 16, 2016) |
| All-time low | $0.7171 (Oct 23, 2024) |
| 52-week high | $1.0413 |
| 52-week low | $0.9281 |
| Median price | $1.0362 |
| Average price | $1.0056 |
| Largest weekly change | +28.9% (Nov 20, 2024) |
| Weeks tracked | 329 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Actavis Pharma, Inc. manufacturer profile
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Drug market
Alprazolam market comparison
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Therapeutic class
Benzodiazepine class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ALPRAZOLAM ODT 0.25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for ALPRAZOLAM ODT 0.25 MG TAB, manufactured by Actavis Pharma, Inc., is $0.9697 per EA (NDC 00228401911), effective Sep 30, 2026.
How has the price of ALPRAZOLAM ODT 0.25 MG TAB changed over time?
Over the history we have for it, the NADAC for ALPRAZOLAM ODT 0.25 MG TAB has declined 10.2%. It has been tracked across 329 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ALPRAZOLAM ODT 0.25 MG TAB?
Since Nov 28, 2013, the NADAC for ALPRAZOLAM ODT 0.25 MG TAB has ranged from a low of $0.7171 (Oct 23, 2024) to a high of $1.1305 (Nov 16, 2016), with a median of $1.0362 per EA.
Are there cheaper alternatives to ALPRAZOLAM ODT 0.25 MG TAB?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALPRAZOLAM 0.25 MG TABLET, is $0.0236 per EA — about 98% below ALPRAZOLAM ODT 0.25 MG TAB.
Who manufactures ALPRAZOLAM ODT 0.25 MG TAB?
ALPRAZOLAM ODT 0.25 MG TAB (NDC 00228401911) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.