Product Information

CHLORZOXAZONE 375 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.6665 per EA under NDC 00254205301. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Nov 2, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CHLORZOXAZONE 375 MG TABLET

Chlorzoxazone
$0.6665per EA

Strength

375 mg/1

Manufacturer

Endo USA Inc.

NDC

00254205301

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CHLORZOXAZONE

Approval Type

Generic (ANDA)

FDA Application

ANDA212743

FDA Approved

11/2/2020

TE Code

AB

On Market Since

6/17/2021

Pharmacological Classes

Centrally-mediated Muscle Relaxation
Muscle Relaxant

Price Statistics

The NADAC for CHLORZOXAZONE 375 MG TABLET has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 67.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.6665 per EA
All-time high$2.1766 (Apr 16, 2025)
All-time low$0.5098 (Feb 18, 2026)
52-week high$0.6665
52-week low$0.5098
Median price$0.6540
Average price$1.2572
Largest weekly change-68.2% (Apr 23, 2025)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+6.7%

1M

+6.7%

3M

+23.7%

6M

+30.7%

1Y

+17.8%

3Y

N/A

5Y

N/A

All

-67.4%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Chlorzoxazone market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of CHLORZOXAZONE 375 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CHLORZOXAZONE 375 MG TABLET, manufactured by Endo USA Inc., is $0.6665 per EA (NDC 00254205301), effective Aug 19, 2026.

How has the price of CHLORZOXAZONE 375 MG TABLET changed over time?

Over the history we have for it, the NADAC for CHLORZOXAZONE 375 MG TABLET has declined 67.4%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for CHLORZOXAZONE 375 MG TABLET?

Since Apr 17, 2024, the NADAC for CHLORZOXAZONE 375 MG TABLET has ranged from a low of $0.5098 (Feb 18, 2026) to a high of $2.1766 (Apr 16, 2025), with a median of $0.6540 per EA.

Are there cheaper alternatives to CHLORZOXAZONE 375 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of CHLORZOXAZONE 375 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures CHLORZOXAZONE 375 MG TABLET?

CHLORZOXAZONE 375 MG TABLET (NDC 00254205301) is labeled by Endo USA Inc., and CMS classifies it as a generic product.