Product Information

CHLORDIAZEPOX-AMITRIPTYL 10-25 is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $1.5774 per EA under NDC 00378027701. Its NADAC has been published 416 times since Nov 28, 2013.

FDA first approved this application on Dec 10, 1986.

CHLORDIAZEPOX-AMITRIPTYL 10-25

chlordiazepoxide and amitriptyline hydrochloride
$1.5774per EA
DEA Schedule CIV

Strength

27.98; 10 mg/1; mg/1

NDC

00378027701

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

6/18/2025

Approval Type

Generic (ANDA)

FDA Application

ANDA071297

FDA Approved

12/10/1986

On Market Since

12/10/1986

Pharmacological Classes

Price Statistics

The NADAC for CHLORDIAZEPOX-AMITRIPTYL 10-25 has been published 416 times since Nov 28, 2013, and over the history we have for it it has risen 24.9%. The table below summarizes its recorded NADAC range and movement.

Current price$1.5774 per EA
All-time high$1.7522 (Sep 10, 2014)
All-time low$1.2629 (Nov 28, 2013)
52-week high$1.5774
52-week low$1.5774
Median price$1.6331
Average price$1.6126
Largest weekly change+13.8% (Jul 23, 2014)
Weeks tracked416
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

0.0%

6M

0.0%

1Y

0.0%

3Y

-5.1%

5Y

-5.1%

All

+24.9%

Last surveyed Jun 10, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CHLORDIAZEPOX-AMITRIPTYL 10-25?

The current National Average Drug Acquisition Cost (NADAC) for CHLORDIAZEPOX-AMITRIPTYL 10-25, manufactured by Mylan Pharmaceuticals Inc., is $1.5774 per EA (NDC 00378027701), effective Jun 10, 2026.

How has the price of CHLORDIAZEPOX-AMITRIPTYL 10-25 changed over time?

Over the history we have for it, the NADAC for CHLORDIAZEPOX-AMITRIPTYL 10-25 has risen 24.9%. It has been tracked across 416 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for CHLORDIAZEPOX-AMITRIPTYL 10-25?

Since Nov 28, 2013, the NADAC for CHLORDIAZEPOX-AMITRIPTYL 10-25 has ranged from a low of $1.2629 (Nov 28, 2013) to a high of $1.7522 (Sep 10, 2014), with a median of $1.6331 per EA.

Are there cheaper alternatives to CHLORDIAZEPOX-AMITRIPTYL 10-25?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as CHLORDIAZEPOX-AMITRIPTYL 10-25 in a comparable dosage form, but none are currently priced below it.

Who manufactures CHLORDIAZEPOX-AMITRIPTYL 10-25?

CHLORDIAZEPOX-AMITRIPTYL 10-25 (NDC 00378027701) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.