Product Information

ATOVAQUONE-PROGUANIL 62.5-25 is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $1.0400 per EA under NDC 00378416001. Its NADAC has been published 478 times since Aug 6, 2014.

FDA first approved this application on May 27, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The Low Outlier badge above means this manufacturer's average price in the atovaquone and proguanil hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ATOVAQUONE-PROGUANIL 62.5-25

atovaquone and proguanil hydrochloride
$1.0400per EA
Low Outlier

Strength

62.5; 25 mg/1; mg/1

NDC

00378416001

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202362

FDA Approved

5/27/2014

TE Code

AB

On Market Since

5/28/2014

Pharmacological Classes

Antimalarial
Antimalarial
Antiprotozoal
Dihydrofolate Reductase Inhibitors

Price Statistics

The NADAC for ATOVAQUONE-PROGUANIL 62.5-25 has been published 478 times since Aug 6, 2014, and over the history we have for it it has declined 44.8%. The table below summarizes its recorded NADAC range and movement.

Current price$1.0400 per EA
All-time high$1.9634 (Mar 11, 2015)
All-time low$0.6264 (Sep 21, 2022)
52-week high$1.3157
52-week low$1.0400
Median price$1.3863
Average price$1.3912
Largest weekly change-62.2% (Sep 21, 2022)
Weeks tracked478
Tracking sinceAug 6, 2014

Price History

1W

-9.1%

1M

-9.1%

3M

-19.3%

6M

-15.2%

1Y

-19.8%

3Y

-15.2%

5Y

-37.2%

All

-44.8%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the atovaquone and proguanil hydrochloride market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of ATOVAQUONE-PROGUANIL 62.5-25?

The current National Average Drug Acquisition Cost (NADAC) for ATOVAQUONE-PROGUANIL 62.5-25, manufactured by Mylan Pharmaceuticals Inc., is $1.0400 per EA (NDC 00378416001), effective Aug 19, 2026.

How has the price of ATOVAQUONE-PROGUANIL 62.5-25 changed over time?

Over the history we have for it, the NADAC for ATOVAQUONE-PROGUANIL 62.5-25 has declined 44.8%. It has been tracked across 478 weekly CMS publications since Aug 6, 2014.

What are the highest and lowest recorded NADAC prices for ATOVAQUONE-PROGUANIL 62.5-25?

Since Aug 6, 2014, the NADAC for ATOVAQUONE-PROGUANIL 62.5-25 has ranged from a low of $0.6264 (Sep 21, 2022) to a high of $1.9634 (Mar 11, 2015), with a median of $1.3863 per EA.

Are there cheaper alternatives to ATOVAQUONE-PROGUANIL 62.5-25?

No other NADAC-published product currently shares the active ingredient and strength of ATOVAQUONE-PROGUANIL 62.5-25 in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ATOVAQUONE-PROGUANIL 62.5-25?

ATOVAQUONE-PROGUANIL 62.5-25 (NDC 00378416001) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.