Product Information
ETHYNODIOL-ETH ESTRA 1 MG-50 MCG is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.7382 per EA under NDC 00378730653. Its NADAC has been published 502 times since Jan 11, 2017.
FDA first approved this application on Feb 9, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378730653
Classification
Generic
Dosage Form
KIT
Effective Date
12/17/2025
Approval Type
Generic (ANDA)
FDA Application
ANDA204704FDA Approved
2/9/2016
TE Code
AB
On Market Since
11/30/2016
Price Statistics
The NADAC for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG has been published 502 times since Jan 11, 2017, and over the history we have for it it has risen 5.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7382 per EA |
|---|---|
| All-time high | $0.8225 (Jan 16, 2019) |
| All-time low | $0.4868 (Feb 19, 2025) |
| 52-week high | $0.7382 |
| 52-week low | $0.7001 |
| Median price | $0.7333 |
| Average price | $0.7031 |
| Largest weekly change | +33.1% (Jul 17, 2019) |
| Weeks tracked | 502 |
| Tracking since | Jan 11, 2017 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
The current National Average Drug Acquisition Cost (NADAC) for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG, manufactured by Mylan Pharmaceuticals Inc., is $0.7382 per EA (NDC 00378730653), effective Aug 19, 2026.
How has the price of ETHYNODIOL-ETH ESTRA 1 MG-50 MCG changed over time?
Over the history we have for it, the NADAC for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG has risen 5.0%. It has been tracked across 502 weekly CMS publications since Jan 11, 2017.
What are the highest and lowest recorded NADAC prices for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
Since Jan 11, 2017, the NADAC for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG has ranged from a low of $0.4868 (Feb 19, 2025) to a high of $0.8225 (Jan 16, 2019), with a median of $0.7333 per EA.
Are there cheaper alternatives to ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ETHYNODIOL-ETH ESTRA 1 MG-35 MCG, is $0.3819 per EA — about 48% below ETHYNODIOL-ETH ESTRA 1 MG-50 MCG.
Who manufactures ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
ETHYNODIOL-ETH ESTRA 1 MG-50 MCG (NDC 00378730653) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.