Product Information
ETHYNODIOL-ETH ESTRA 1 MG-50 MCG is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.7382 per EA under NDC 00378730653. Its NADAC has been published 502 times since Jan 11, 2017.
FDA first approved this application on Feb 9, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378730653
Classification
Generic
Dosage Form
KIT
Effective Date
12/17/2025
Approval Type
Generic (ANDA)
FDA Application
ANDA204704FDA Approved
2/9/2016
TE Code
AB
On Market Since
11/30/2016
Price Statistics
The NADAC for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG has been published 502 times since Jan 11, 2017, and over the history we have for it it has risen 5.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7382 per EA |
|---|---|
| All-time high | $0.8225 (Jan 16, 2019) |
| All-time low | $0.4868 (Feb 19, 2025) |
| 52-week high | $0.7382 |
| 52-week low | $0.7272 |
| Median price | $0.7333 |
| Average price | $0.7031 |
| Largest weekly change | +33.1% (Jul 17, 2019) |
| Weeks tracked | 502 |
| Tracking since | Jan 11, 2017 |
1W
N/A
1M
N/A
3M
0.0%
6M
0.0%
1Y
+1.5%
3Y
+6.3%
5Y
-1.7%
All
+5.0%
Last surveyed Aug 19, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
ethynodiol diacetate and ethinyl estradiol market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
The current National Average Drug Acquisition Cost (NADAC) for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG, manufactured by Mylan Pharmaceuticals Inc., is $0.7382 per EA (NDC 00378730653), effective Aug 19, 2026.
How has the price of ETHYNODIOL-ETH ESTRA 1 MG-50 MCG changed over time?
Over the history we have for it, the NADAC for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG has risen 5.0%. It has been tracked across 502 weekly CMS publications since Jan 11, 2017.
What are the highest and lowest recorded NADAC prices for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
Since Jan 11, 2017, the NADAC for ETHYNODIOL-ETH ESTRA 1 MG-50 MCG has ranged from a low of $0.4868 (Feb 19, 2025) to a high of $0.8225 (Jan 16, 2019), with a median of $0.7333 per EA.
Are there cheaper alternatives to ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ETHYNODIOL-ETH ESTRA 1 MG-35 MCG, is $0.3819 per EA — about 48% below ETHYNODIOL-ETH ESTRA 1 MG-50 MCG.
Who manufactures ETHYNODIOL-ETH ESTRA 1 MG-50 MCG?
ETHYNODIOL-ETH ESTRA 1 MG-50 MCG (NDC 00378730653) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.