Product Information
CYCLOSPORINE 0.05% EYE EMULSION is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $1.2396 per EA under NDC 00378876058. Its NADAC has been published 210 times since Aug 17, 2022.
FDA first approved this application on Feb 2, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/mL
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378876058
Classification
Generic
Dosage Form
EMULSION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
CYCLOSPORINEApproval Type
Generic (ANDA)
FDA Application
ANDA205894FDA Approved
2/2/2022
TE Code
AB
On Market Since
2/3/2022
Pharmacological Classes
Price Statistics
The NADAC for CYCLOSPORINE 0.05% EYE EMULSION has been published 210 times since Aug 17, 2022, and over the history we have for it it has declined 78.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.2396 per EA |
|---|---|
| All-time high | $5.9024 (Nov 16, 2022) |
| All-time low | $1.2189 (Jul 22, 2026) |
| 52-week high | $2.0995 |
| 52-week low | $1.2189 |
| Median price | $2.5696 |
| Average price | $2.8078 |
| Largest weekly change | -24.6% (Apr 17, 2024) |
| Weeks tracked | 210 |
| Tracking since | Aug 17, 2022 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 25% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CYCLOSPORINE 0.05% EYE EMULSION?
The current National Average Drug Acquisition Cost (NADAC) for CYCLOSPORINE 0.05% EYE EMULSION, manufactured by Mylan Pharmaceuticals Inc., is $1.2396 per EA (NDC 00378876058), effective Aug 19, 2026.
How has the price of CYCLOSPORINE 0.05% EYE EMULSION changed over time?
Over the history we have for it, the NADAC for CYCLOSPORINE 0.05% EYE EMULSION has declined 78.8%. It has been tracked across 210 weekly CMS publications since Aug 17, 2022.
What are the highest and lowest recorded NADAC prices for CYCLOSPORINE 0.05% EYE EMULSION?
Since Aug 17, 2022, the NADAC for CYCLOSPORINE 0.05% EYE EMULSION has ranged from a low of $1.2189 (Jul 22, 2026) to a high of $5.9024 (Nov 16, 2022), with a median of $2.5696 per EA.
Are there cheaper alternatives to CYCLOSPORINE 0.05% EYE EMULSION?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CYCLOSPORINE 0.05% EYE EMULSION, is $0.9240 per EA — about 25% below CYCLOSPORINE 0.05% EYE EMULSION.
Who manufactures CYCLOSPORINE 0.05% EYE EMULSION?
CYCLOSPORINE 0.05% EYE EMULSION (NDC 00378876058) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.