Product Information

BUPROPION HCL SR 200 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.1087 per EA under NDC 00591354260. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Mar 24, 2009. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 200 MG TABLET

bupropion hydrochloride
$0.1087per EA

Strength

200 mg/1

NDC

00591354260

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA079095

FDA Approved

3/24/2009

TE Code

AB1

On Market Since

7/2/2009

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 200 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 73.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1087 per EA
All-time high$0.5041 (Feb 12, 2014)
All-time low$0.1002 (Nov 19, 2025)
52-week high$0.1380
52-week low$0.1002
Median price$0.2203
Average price$0.2355
Largest weekly change+39.8% (May 19, 2021)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-2.0%

1M

-2.0%

3M

+0.3%

6M

-5.4%

1Y

-26.4%

3Y

-22.7%

5Y

-40.1%

All

-73.8%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 200 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 200 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.1087 per EA (NDC 00591354260), effective Aug 19, 2026.

How has the price of BUPROPION HCL SR 200 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 200 MG TABLET has declined 73.8%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 200 MG TABLET?

Since Nov 28, 2013, the NADAC for BUPROPION HCL SR 200 MG TABLET has ranged from a low of $0.1002 (Nov 19, 2025) to a high of $0.5041 (Feb 12, 2014), with a median of $0.2203 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 200 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 200 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 200 MG TABLET?

BUPROPION HCL SR 200 MG TABLET (NDC 00591354260) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.