Product Information
SERTRALINE HCL 50 MG TABLET is a generic product labeled by Accord Healthcare Inc., priced at $0.0346 per EA under NDC 16729021615. Its NADAC has been published 482 times since Mar 1, 2017.
FDA first approved this application on Nov 7, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Accord Healthcare Inc.NDC
16729021615
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
5/20/2026
Active Ingredients
SERTRALINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA202825FDA Approved
11/7/2014
TE Code
AB
On Market Since
2/9/2017
Pharmacological Classes
Price Statistics
The NADAC for SERTRALINE HCL 50 MG TABLET has been published 482 times since Mar 1, 2017, and over the history we have for it it has declined 26.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0346 per EA |
|---|---|
| All-time high | $0.0691 (Aug 12, 2020) |
| All-time low | $0.0292 (Nov 20, 2024) |
| 52-week high | $0.0388 |
| 52-week low | $0.0345 |
| Median price | $0.0438 |
| Average price | $0.0434 |
| Largest weekly change | +57.1% (Jul 22, 2020) |
| Weeks tracked | 482 |
| Tracking since | Mar 1, 2017 |
1W
N/A
1M
N/A
3M
N/A
6M
-4.6%
1Y
-4.1%
3Y
-24.7%
5Y
-28.2%
All
-26.3%
Last surveyed May 20, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SERTRALINE HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 50 MG TABLET, manufactured by Accord Healthcare Inc., is $0.0346 per EA (NDC 16729021615), effective May 20, 2026.
How has the price of SERTRALINE HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for SERTRALINE HCL 50 MG TABLET has declined 26.3%. It has been tracked across 482 weekly CMS publications since Mar 1, 2017.
What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 50 MG TABLET?
Since Mar 1, 2017, the NADAC for SERTRALINE HCL 50 MG TABLET has ranged from a low of $0.0292 (Nov 20, 2024) to a high of $0.0691 (Aug 12, 2020), with a median of $0.0438 per EA.
Are there cheaper alternatives to SERTRALINE HCL 50 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SERTRALINE HCL 50 MG TABLET?
SERTRALINE HCL 50 MG TABLET (NDC 16729021615) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.