Product Information
CLOBETASOL 0.05% OINTMENT is a generic product labeled by Encube Ethicals, Inc., priced at $0.1183 per GM under NDC 21922001706. Its NADAC has been published 342 times since Feb 5, 2020.
FDA first approved this application on Nov 15, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922001706
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA211295FDA Approved
11/15/2019
TE Code
AB
On Market Since
11/18/2019
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% OINTMENT has been published 342 times since Feb 5, 2020, and over the history we have for it it has declined 78.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1183 per GM |
|---|---|
| All-time high | $0.5810 (Mar 10, 2021) |
| All-time low | $0.0961 (Nov 20, 2024) |
| 52-week high | $0.1801 |
| 52-week low | $0.1033 |
| Median price | $0.1938 |
| Average price | $0.2648 |
| Largest weekly change | +61.0% (Apr 21, 2021) |
| Weeks tracked | 342 |
| Tracking since | Feb 5, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% OINTMENT, manufactured by Encube Ethicals, Inc., is $0.1183 per GM (NDC 21922001706), effective Aug 19, 2026.
How has the price of CLOBETASOL 0.05% OINTMENT changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% OINTMENT has declined 78.8%. It has been tracked across 342 weekly CMS publications since Feb 5, 2020.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% OINTMENT?
Since Feb 5, 2020, the NADAC for CLOBETASOL 0.05% OINTMENT has ranged from a low of $0.0961 (Nov 20, 2024) to a high of $0.5810 (Mar 10, 2021), with a median of $0.1938 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% OINTMENT?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% OINTMENT, is $0.1124 per GM — about 5% below CLOBETASOL 0.05% OINTMENT.
Who manufactures CLOBETASOL 0.05% OINTMENT?
CLOBETASOL 0.05% OINTMENT (NDC 21922001706) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.