Product Information
TESTOSTERONE 12.5 MG/1.25 GRAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.8264 per GM under NDC 21922001947. Its NADAC has been published 66 times since Jul 2, 2025.
FDA first approved this application on Nov 9, 2021. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922001947
Classification
Generic
Dosage Form
GEL
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
TESTOSTERONEApproval Type
Generic (ANDA)
FDA Application
ANDA212984FDA Approved
11/9/2021
TE Code
AB1
On Market Since
1/10/2021
Pharmacological Classes
Price Statistics
The NADAC for TESTOSTERONE 12.5 MG/1.25 GRAM has been published 66 times since Jul 2, 2025, and over the history we have for it it has declined 21.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8264 per GM |
|---|---|
| All-time high | $1.0534 (Jul 16, 2025) |
| All-time low | $0.6126 (Jul 22, 2026) |
| 52-week high | $1.0033 |
| 52-week low | $0.6126 |
| Median price | $0.8610 |
| Average price | $0.8408 |
| Largest weekly change | +17.5% (Aug 19, 2026) |
| Weeks tracked | 66 |
| Tracking since | Jul 2, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 51% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Encube Ethicals, Inc. manufacturer profile
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Drug market
Testosterone Gel, 1% market comparison
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Therapeutic class
Androgen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TESTOSTERONE 12.5 MG/1.25 GRAM?
The current National Average Drug Acquisition Cost (NADAC) for TESTOSTERONE 12.5 MG/1.25 GRAM, manufactured by Encube Ethicals, Inc., is $0.8264 per GM (NDC 21922001947), effective Sep 30, 2026.
How has the price of TESTOSTERONE 12.5 MG/1.25 GRAM changed over time?
Over the history we have for it, the NADAC for TESTOSTERONE 12.5 MG/1.25 GRAM has declined 21.5%. It has been tracked across 66 weekly CMS publications since Jul 2, 2025.
What are the highest and lowest recorded NADAC prices for TESTOSTERONE 12.5 MG/1.25 GRAM?
Since Jul 2, 2025, the NADAC for TESTOSTERONE 12.5 MG/1.25 GRAM has ranged from a low of $0.6126 (Jul 22, 2026) to a high of $1.0534 (Jul 16, 2025), with a median of $0.8610 per GM.
Are there cheaper alternatives to TESTOSTERONE 12.5 MG/1.25 GRAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TESTOSTERONE 1% (50 MG/5 G) PK, is $0.4061 per GM — about 51% below TESTOSTERONE 12.5 MG/1.25 GRAM.
Who manufactures TESTOSTERONE 12.5 MG/1.25 GRAM?
TESTOSTERONE 12.5 MG/1.25 GRAM (NDC 21922001947) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.