Product Information
METRONIDAZOLE TOPICAL 0.75% GL is a generic product labeled by Encube Ethicals, Inc., priced at $0.1793 per GM under NDC 21922007006. Its NADAC has been published 80 times since Mar 26, 2025.
FDA first approved this application on Jul 13, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
7.5 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922007006
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
METRONIDAZOLEApproval Type
Generic (ANDA)
FDA Application
ANDA077547FDA Approved
7/13/2006
TE Code
AB
On Market Since
1/28/2025
Pharmacological Classes
Price Statistics
The NADAC for METRONIDAZOLE TOPICAL 0.75% GL has been published 80 times since Mar 26, 2025, and over the history we have for it it has declined 59.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1793 per GM |
|---|---|
| All-time high | $0.4429 (May 14, 2025) |
| All-time low | $0.1793 (Sep 23, 2026) |
| 52-week high | $0.4059 |
| 52-week low | $0.1793 |
| Median price | $0.3539 |
| Average price | $0.3563 |
| Largest weekly change | -18.9% (Aug 19, 2026) |
| Weeks tracked | 80 |
| Tracking since | Mar 26, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Metronidazole Topical market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Encube Ethicals, Inc. manufacturer profile
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Drug market
Metronidazole Topical market comparison
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Therapeutic class
Nitroimidazole Antimicrobial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of METRONIDAZOLE TOPICAL 0.75% GL?
The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE TOPICAL 0.75% GL, manufactured by Encube Ethicals, Inc., is $0.1793 per GM (NDC 21922007006), effective Sep 30, 2026.
How has the price of METRONIDAZOLE TOPICAL 0.75% GL changed over time?
Over the history we have for it, the NADAC for METRONIDAZOLE TOPICAL 0.75% GL has declined 59.0%. It has been tracked across 80 weekly CMS publications since Mar 26, 2025.
What are the highest and lowest recorded NADAC prices for METRONIDAZOLE TOPICAL 0.75% GL?
Since Mar 26, 2025, the NADAC for METRONIDAZOLE TOPICAL 0.75% GL has ranged from a low of $0.1793 (Sep 23, 2026) to a high of $0.4429 (May 14, 2025), with a median of $0.3539 per GM.
Are there cheaper alternatives to METRONIDAZOLE TOPICAL 0.75% GL?
No other NADAC-published product currently shares the active ingredient and strength of METRONIDAZOLE TOPICAL 0.75% GL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures METRONIDAZOLE TOPICAL 0.75% GL?
METRONIDAZOLE TOPICAL 0.75% GL (NDC 21922007006) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.