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Product Information

METRONIDAZOLE TOPICAL 0.75% GL is a generic product labeled by Encube Ethicals, Inc., priced at $0.2209 per GM under NDC 21922007006. Its NADAC has been published 74 times since Mar 26, 2025.

FDA first approved this application on Jul 13, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METRONIDAZOLE TOPICAL 0.75% GL

Metronidazole Topical
$0.2209per GM

Strength

7.5 mg/g

NDC

21922007006

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

METRONIDAZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA077547

FDA Approved

7/13/2006

TE Code

AB

On Market Since

1/28/2025

Pharmacological Classes

Nitroimidazole Antimicrobial
Nitroimidazoles

Price Statistics

The NADAC for METRONIDAZOLE TOPICAL 0.75% GL has been published 74 times since Mar 26, 2025, and over the history we have for it it has declined 49.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2209 per GM
All-time high$0.4429 (May 14, 2025)
All-time low$0.2209 (Aug 19, 2026)
52-week high$0.4207
52-week low$0.2209
Median price$0.3647
Average price$0.3684
Largest weekly change-18.9% (Aug 19, 2026)
Weeks tracked74
Tracking sinceMar 26, 2025

Price History

1W

-18.9%

1M

-31.5%

3M

-37.6%

6M

-30.3%

1Y

-42.9%

3Y

N/A

5Y

N/A

All

-49.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Metronidazole Topical market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of METRONIDAZOLE TOPICAL 0.75% GL?

The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE TOPICAL 0.75% GL, manufactured by Encube Ethicals, Inc., is $0.2209 per GM (NDC 21922007006), effective Aug 19, 2026.

How has the price of METRONIDAZOLE TOPICAL 0.75% GL changed over time?

Over the history we have for it, the NADAC for METRONIDAZOLE TOPICAL 0.75% GL has declined 49.5%. It has been tracked across 74 weekly CMS publications since Mar 26, 2025.

What are the highest and lowest recorded NADAC prices for METRONIDAZOLE TOPICAL 0.75% GL?

Since Mar 26, 2025, the NADAC for METRONIDAZOLE TOPICAL 0.75% GL has ranged from a low of $0.2209 (Aug 19, 2026) to a high of $0.4429 (May 14, 2025), with a median of $0.3647 per GM.

Are there cheaper alternatives to METRONIDAZOLE TOPICAL 0.75% GL?

No other NADAC-published product currently shares the active ingredient and strength of METRONIDAZOLE TOPICAL 0.75% GL in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures METRONIDAZOLE TOPICAL 0.75% GL?

METRONIDAZOLE TOPICAL 0.75% GL (NDC 21922007006) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.