Product Information
DONEPEZIL HCL 23 MG TABLET is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $0.7291 per EA under NDC 24979000406. Its NADAC has been published 590 times since May 6, 2015.
FDA first approved this application on Oct 29, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Donepezil Hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
23 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
24979000406
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DONEPEZIL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA203104FDA Approved
10/29/2014
TE Code
AB
On Market Since
3/1/2015
Pharmacological Classes
Price Statistics
The NADAC for DONEPEZIL HCL 23 MG TABLET has been published 590 times since May 6, 2015, and over the history we have for it it has declined 89.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7291 per EA |
|---|---|
| All-time high | $7.2404 (Jul 15, 2015) |
| All-time low | $0.5251 (Apr 20, 2022) |
| 52-week high | $0.8411 |
| 52-week low | $0.6722 |
| Median price | $0.8957 |
| Average price | $1.6868 |
| Largest weekly change | +59.9% (Feb 23, 2022) |
| Weeks tracked | 590 |
| Tracking since | May 6, 2015 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DONEPEZIL HCL 23 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for DONEPEZIL HCL 23 MG TABLET, manufactured by Upsher-Smith Laboratories LLC, is $0.7291 per EA (NDC 24979000406), effective Aug 19, 2026.
How has the price of DONEPEZIL HCL 23 MG TABLET changed over time?
Over the history we have for it, the NADAC for DONEPEZIL HCL 23 MG TABLET has declined 89.8%. It has been tracked across 590 weekly CMS publications since May 6, 2015.
What are the highest and lowest recorded NADAC prices for DONEPEZIL HCL 23 MG TABLET?
Since May 6, 2015, the NADAC for DONEPEZIL HCL 23 MG TABLET has ranged from a low of $0.5251 (Apr 20, 2022) to a high of $7.2404 (Jul 15, 2015), with a median of $0.8957 per EA.
Are there cheaper alternatives to DONEPEZIL HCL 23 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DONEPEZIL HCL 23 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures DONEPEZIL HCL 23 MG TABLET?
DONEPEZIL HCL 23 MG TABLET (NDC 24979000406) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.