This NDC is on FDA's drug shortage list (posted Apr 2, 2020)
Reported reason: Other
Product Information
MIDAZOLAM HCL 50 MG/10 ML VIAL is a generic product labeled by Sagent Pharmaceuticals, priced at $0.4500 per ML under NDC 25021066110. Its NADAC has been published 139 times since Jan 22, 2014.
FDA first approved this application on Jan 25, 2012. Its Orange Book therapeutic-equivalence code is AP.
Strength
5 mg/mL
Manufacturer
Sagent PharmaceuticalsNDC
25021066110
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
5/21/2025
Active Ingredients
MIDAZOLAM HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090850FDA Approved
1/25/2012
TE Code
AP
On Market Since
3/19/2012
Pharmacological Classes
Price Statistics
The NADAC for MIDAZOLAM HCL 50 MG/10 ML VIAL has been published 139 times since Jan 22, 2014, and over the history we have for it it has declined 37.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4500 per ML |
|---|---|
| All-time high | $0.7147 (Nov 12, 2014) |
| All-time low | $0.4106 (Nov 19, 2014) |
| 52-week high | $0.4500 |
| 52-week low | $0.4500 |
| Median price | $0.4500 |
| Average price | $0.5157 |
| Largest weekly change | -42.5% (Nov 19, 2014) |
| Weeks tracked | 139 |
| Tracking since | Jan 22, 2014 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
+9.6%
5Y
+9.6%
All
-37.0%
Last surveyed Feb 11, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the midazolam hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MIDAZOLAM HCL 50 MG/10 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for MIDAZOLAM HCL 50 MG/10 ML VIAL, manufactured by Sagent Pharmaceuticals, is $0.4500 per ML (NDC 25021066110), effective Feb 11, 2026.
How has the price of MIDAZOLAM HCL 50 MG/10 ML VIAL changed over time?
Over the history we have for it, the NADAC for MIDAZOLAM HCL 50 MG/10 ML VIAL has declined 37.0%. It has been tracked across 139 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for MIDAZOLAM HCL 50 MG/10 ML VIAL?
Since Jan 22, 2014, the NADAC for MIDAZOLAM HCL 50 MG/10 ML VIAL has ranged from a low of $0.4106 (Nov 19, 2014) to a high of $0.7147 (Nov 12, 2014), with a median of $0.4500 per ML.
Are there cheaper alternatives to MIDAZOLAM HCL 50 MG/10 ML VIAL?
No other NADAC-published product currently shares the active ingredient and strength of MIDAZOLAM HCL 50 MG/10 ML VIAL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures MIDAZOLAM HCL 50 MG/10 ML VIAL?
MIDAZOLAM HCL 50 MG/10 ML VIAL (NDC 25021066110) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.
Is MIDAZOLAM HCL 50 MG/10 ML VIAL in shortage?
Yes — NDC 25021066110 is currently listed in FDA's drug shortage database (posted Apr 2, 2020). Reported reason: Other.