Product Information
BUPROPION HCL SR 200 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.1087 per EA under NDC 42806041160. Its NADAC has been published 233 times since Mar 9, 2022.
FDA first approved this application on Nov 25, 2003. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
200 mg/1
Manufacturer
Epic Pharma LLCNDC
42806041160
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075932FDA Approved
11/25/2003
TE Code
AB1
On Market Since
12/15/2021
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL SR 200 MG TABLET has been published 233 times since Mar 9, 2022, and over the history we have for it it has declined 31.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1087 per EA |
|---|---|
| All-time high | $0.1868 (Sep 13, 2023) |
| All-time low | $0.1002 (Nov 19, 2025) |
| 52-week high | $0.1380 |
| 52-week low | $0.1002 |
| Median price | $0.1389 |
| Average price | $0.1351 |
| Largest weekly change | +32.7% (Aug 23, 2023) |
| Weeks tracked | 233 |
| Tracking since | Mar 9, 2022 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPROPION HCL SR 200 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 200 MG TABLET, manufactured by Epic Pharma LLC, is $0.1087 per EA (NDC 42806041160), effective Aug 19, 2026.
How has the price of BUPROPION HCL SR 200 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL SR 200 MG TABLET has declined 31.1%. It has been tracked across 233 weekly CMS publications since Mar 9, 2022.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 200 MG TABLET?
Since Mar 9, 2022, the NADAC for BUPROPION HCL SR 200 MG TABLET has ranged from a low of $0.1002 (Nov 19, 2025) to a high of $0.1868 (Sep 13, 2023), with a median of $0.1389 per EA.
Are there cheaper alternatives to BUPROPION HCL SR 200 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 200 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL SR 200 MG TABLET?
BUPROPION HCL SR 200 MG TABLET (NDC 42806041160) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.