Product Information
ORPHENADRINE ER 100 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.4536 per EA under NDC 43386048026. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Jun 19, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Lupin Pharmaceuticals Inc.NDC
43386048026
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ORPHENADRINE CITRATEApproval Type
Generic (ANDA)
FDA Application
ANDA040284FDA Approved
6/19/1998
TE Code
AB
On Market Since
6/19/1998
Pharmacological Classes
Price Statistics
The NADAC for ORPHENADRINE ER 100 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 21.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4536 per EA |
|---|---|
| All-time high | $0.5364 (Dec 14, 2022) |
| All-time low | $0.2632 (Jan 22, 2020) |
| 52-week high | $0.4750 |
| 52-week low | $0.4289 |
| Median price | $0.3891 |
| Average price | $0.3877 |
| Largest weekly change | +70.2% (Aug 19, 2020) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 26% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Lupin Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
ORPHENADRINE CITRATE market comparison
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Therapeutic class
Muscle Relaxant class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ORPHENADRINE ER 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ORPHENADRINE ER 100 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.4536 per EA (NDC 43386048026), effective Sep 30, 2026.
How has the price of ORPHENADRINE ER 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for ORPHENADRINE ER 100 MG TABLET has risen 21.9%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ORPHENADRINE ER 100 MG TABLET?
Since Nov 28, 2013, the NADAC for ORPHENADRINE ER 100 MG TABLET has ranged from a low of $0.2632 (Jan 22, 2020) to a high of $0.5364 (Dec 14, 2022), with a median of $0.3891 per EA.
Are there cheaper alternatives to ORPHENADRINE ER 100 MG TABLET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ORPHENADRINE ER 100 MG TABLET, is $0.3361 per EA — about 26% below ORPHENADRINE ER 100 MG TABLET.
Who manufactures ORPHENADRINE ER 100 MG TABLET?
ORPHENADRINE ER 100 MG TABLET (NDC 43386048026) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.