Product Information

URSODIOL 500 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.6356 per EA under NDC 49884041301. Its NADAC has been published 650 times since Mar 12, 2014.

FDA first approved this application on Feb 14, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

URSODIOL 500 MG TABLET

Ursodiol
$0.6356per EA

Strength

500 mg/1

Manufacturer

Endo USA Inc.

NDC

49884041301

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

URSODIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA202540

FDA Approved

2/14/2013

TE Code

AB

On Market Since

8/1/2013

Pharmacological Classes

Bile Acid
Bile Acids and Salts

Price Statistics

The NADAC for URSODIOL 500 MG TABLET has been published 650 times since Mar 12, 2014, and over the history we have for it it has declined 78.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.6356 per EA
All-time high$3.3502 (Apr 13, 2016)
All-time low$0.5191 (Jul 17, 2024)
52-week high$0.7862
52-week low$0.6355
Median price$1.2516
Average price$1.4947
Largest weekly change-33.1% (Jul 17, 2024)
Weeks tracked650
Tracking sinceMar 12, 2014

Price History

1W

-3.5%

1M

-3.5%

3M

-6.8%

6M

-3.7%

1Y

-19.2%

3Y

-23.4%

5Y

-38.9%

All

-78.8%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of URSODIOL 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for URSODIOL 500 MG TABLET, manufactured by Endo USA Inc., is $0.6356 per EA (NDC 49884041301), effective Aug 19, 2026.

How has the price of URSODIOL 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for URSODIOL 500 MG TABLET has declined 78.8%. It has been tracked across 650 weekly CMS publications since Mar 12, 2014.

What are the highest and lowest recorded NADAC prices for URSODIOL 500 MG TABLET?

Since Mar 12, 2014, the NADAC for URSODIOL 500 MG TABLET has ranged from a low of $0.5191 (Jul 17, 2024) to a high of $3.3502 (Apr 13, 2016), with a median of $1.2516 per EA.

Are there cheaper alternatives to URSODIOL 500 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as URSODIOL 500 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures URSODIOL 500 MG TABLET?

URSODIOL 500 MG TABLET (NDC 49884041301) is labeled by Endo USA Inc., and CMS classifies it as a generic product.