Product Information
URSODIOL 500 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.6471 per EA under NDC 49884041301. Its NADAC has been published 656 times since Mar 12, 2014.
FDA first approved this application on Feb 14, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Endo USA Inc.NDC
49884041301
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
URSODIOLApproval Type
Generic (ANDA)
FDA Application
ANDA202540FDA Approved
2/14/2013
TE Code
AB
On Market Since
8/1/2013
Pharmacological Classes
Price Statistics
The NADAC for URSODIOL 500 MG TABLET has been published 656 times since Mar 12, 2014, and over the history we have for it it has declined 78.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6471 per EA |
|---|---|
| All-time high | $3.3502 (Apr 13, 2016) |
| All-time low | $0.5191 (Jul 17, 2024) |
| 52-week high | $0.7692 |
| 52-week low | $0.6355 |
| Median price | $1.2266 |
| Average price | $1.4869 |
| Largest weekly change | -33.1% (Jul 17, 2024) |
| Weeks tracked | 656 |
| Tracking since | Mar 12, 2014 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Endo USA Inc. manufacturer profile
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Drug market
Ursodiol market comparison
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Therapeutic class
Bile Acid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of URSODIOL 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for URSODIOL 500 MG TABLET, manufactured by Endo USA Inc., is $0.6471 per EA (NDC 49884041301), effective Sep 30, 2026.
How has the price of URSODIOL 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for URSODIOL 500 MG TABLET has declined 78.4%. It has been tracked across 656 weekly CMS publications since Mar 12, 2014.
What are the highest and lowest recorded NADAC prices for URSODIOL 500 MG TABLET?
Since Mar 12, 2014, the NADAC for URSODIOL 500 MG TABLET has ranged from a low of $0.5191 (Jul 17, 2024) to a high of $3.3502 (Apr 13, 2016), with a median of $1.2266 per EA.
Are there cheaper alternatives to URSODIOL 500 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as URSODIOL 500 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures URSODIOL 500 MG TABLET?
URSODIOL 500 MG TABLET (NDC 49884041301) is labeled by Endo USA Inc., and CMS classifies it as a generic product.