Product Information
ENSTILAR 0.005%-0.064% FOAM is a brand product labeled by LEO Pharma Inc., priced at $21.8368 per GM under NDC 50222030260. Its NADAC has been published 540 times since Apr 20, 2016.
FDA first approved this application on Oct 16, 2015.
The High Outlier badge above means this manufacturer's average price in the calcipotriene and betamethasone dipropionate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
.5; 50 mg/g; ug/g
Manufacturer
LEO Pharma Inc.NDC
50222030260
Classification
Brand
Dosage Form
AEROSOL, FOAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
BETAMETHASONE DIPROPIONATE; CALCIPOTRIENE MONOHYDRATEApproval Type
New Drug (NDA)
FDA Application
NDA207589FDA Approved
10/16/2015
On Market Since
10/16/2015
Pharmacological Classes
Price Statistics
The NADAC for ENSTILAR 0.005%-0.064% FOAM has been published 540 times since Apr 20, 2016, and over the history we have for it it has risen 63.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $21.8368 per GM |
|---|---|
| All-time high | $21.8461 (Dec 10, 2025) |
| All-time low | $13.3095 (May 18, 2016) |
| 52-week high | $21.8461 |
| 52-week low | $21.7994 |
| Median price | $18.6917 |
| Average price | $18.3589 |
| Largest weekly change | +9.0% (Jan 10, 2018) |
| Weeks tracked | 540 |
| Tracking since | Apr 20, 2016 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 23% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ENSTILAR 0.005%-0.064% FOAM?
The current National Average Drug Acquisition Cost (NADAC) for ENSTILAR 0.005%-0.064% FOAM, manufactured by LEO Pharma Inc., is $21.8368 per GM (NDC 50222030260), effective Aug 19, 2026.
How has the price of ENSTILAR 0.005%-0.064% FOAM changed over time?
Over the history we have for it, the NADAC for ENSTILAR 0.005%-0.064% FOAM has risen 63.7%. It has been tracked across 540 weekly CMS publications since Apr 20, 2016.
What are the highest and lowest recorded NADAC prices for ENSTILAR 0.005%-0.064% FOAM?
Since Apr 20, 2016, the NADAC for ENSTILAR 0.005%-0.064% FOAM has ranged from a low of $13.3095 (May 18, 2016) to a high of $21.8461 (Dec 10, 2025), with a median of $18.6917 per GM.
Are there cheaper alternatives to ENSTILAR 0.005%-0.064% FOAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ENSTILAR 0.005%-0.064% FOAM, is $16.7274 per GM — about 23% below ENSTILAR 0.005%-0.064% FOAM.
Who manufactures ENSTILAR 0.005%-0.064% FOAM?
ENSTILAR 0.005%-0.064% FOAM (NDC 50222030260) is labeled by LEO Pharma Inc., and CMS classifies it as a brand product.