Product Information
BUPROPION HCL XL 150 MG TABLET is a generic product labeled by ScieGen Pharmaceuticals Inc., priced at $0.0785 per EA under NDC 50228014490. Its NADAC has been published 69 times since Jun 11, 2025.
FDA first approved this application on Apr 12, 2017. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
150 mg/1
Manufacturer
ScieGen Pharmaceuticals Inc.NDC
50228014490
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207479FDA Approved
4/12/2017
TE Code
AB3
On Market Since
4/12/2017
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 69 times since Jun 11, 2025, and over the history we have for it it has declined 25.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0785 per EA |
|---|---|
| All-time high | $0.1048 (Jun 11, 2025) |
| All-time low | $0.0770 (Apr 22, 2026) |
| 52-week high | $0.0996 |
| 52-week low | $0.0770 |
| Median price | $0.0857 |
| Average price | $0.0879 |
| Largest weekly change | -8.4% (Feb 18, 2026) |
| Weeks tracked | 69 |
| Tracking since | Jun 11, 2025 |
Generic Alternatives
The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
ScieGen Pharmaceuticals Inc. manufacturer profile
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Drug market
bupropion hydrochloride market comparison
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Therapeutic class
Aminoketone class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by ScieGen Pharmaceuticals Inc., is $0.0785 per EA (NDC 50228014490), effective Sep 30, 2026.
How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 25.1%. It has been tracked across 69 weekly CMS publications since Jun 11, 2025.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?
Since Jun 11, 2025, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0770 (Apr 22, 2026) to a high of $0.1048 (Jun 11, 2025), with a median of $0.0857 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?
Yes. 14 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 150 MG TABLET, is $0.0779 per EA — about 1% below BUPROPION HCL XL 150 MG TABLET.
Who manufactures BUPROPION HCL XL 150 MG TABLET?
BUPROPION HCL XL 150 MG TABLET (NDC 50228014490) is labeled by ScieGen Pharmaceuticals Inc., and CMS classifies it as a generic product.