Product Information
PRIMIDONE 250 MG TABLET is a generic product labeled by AvPAK, priced at $0.2276 per EA under NDC 50268068715. Its NADAC has been published 464 times since Nov 15, 2017.
FDA first approved this application on Apr 23, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
250 mg/1
Manufacturer
AvPAKNDC
50268068715
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PRIMIDONEApproval Type
Generic (ANDA)
FDA Application
ANDA040866FDA Approved
4/23/2008
TE Code
AB
On Market Since
5/19/2011
Pharmacological Classes
Price Statistics
The NADAC for PRIMIDONE 250 MG TABLET has been published 464 times since Nov 15, 2017, and over the history we have for it it has risen 48.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2276 per EA |
|---|---|
| All-time high | $0.3204 (Jul 13, 2022) |
| All-time low | $0.1484 (Nov 22, 2017) |
| 52-week high | $0.2672 |
| 52-week low | $0.2197 |
| Median price | $0.2610 |
| Average price | $0.2616 |
| Largest weekly change | +31.2% (Aug 21, 2024) |
| Weeks tracked | 464 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 8% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
AvPAK manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Primidone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Anti-epileptic Agent class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PRIMIDONE 250 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PRIMIDONE 250 MG TABLET, manufactured by AvPAK, is $0.2276 per EA (NDC 50268068715), effective Sep 30, 2026.
How has the price of PRIMIDONE 250 MG TABLET changed over time?
Over the history we have for it, the NADAC for PRIMIDONE 250 MG TABLET has risen 48.4%. It has been tracked across 464 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for PRIMIDONE 250 MG TABLET?
Since Nov 15, 2017, the NADAC for PRIMIDONE 250 MG TABLET has ranged from a low of $0.1484 (Nov 22, 2017) to a high of $0.3204 (Jul 13, 2022), with a median of $0.2610 per EA.
Are there cheaper alternatives to PRIMIDONE 250 MG TABLET?
Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PRIMIDONE 250 MG TABLET, is $0.2102 per EA — about 8% below PRIMIDONE 250 MG TABLET.
Who manufactures PRIMIDONE 250 MG TABLET?
PRIMIDONE 250 MG TABLET (NDC 50268068715) is labeled by AvPAK, and CMS classifies it as a generic product.