Product Information
YAZ 28 TABLET is a brand product labeled by Bayer HealthCare Pharmaceuticals Inc., priced at $5.8438 per EA under NDC 50419040503. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Mar 16, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Drospirenone and ethinyl estradiol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Manufacturer
Bayer HealthCare Pharmaceuticals Inc.NDC
50419040503
Classification
Brand
Dosage Form
KIT
Effective Date
9/23/2026
Approval Type
New Drug (NDA)
FDA Application
NDA021676FDA Approved
3/16/2006
TE Code
AB
On Market Since
3/16/2006
Price Statistics
The NADAC for YAZ 28 TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 114.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.8438 per EA |
|---|---|
| All-time high | $5.8909 (Oct 11, 2023) |
| All-time low | $2.6654 (Jul 23, 2014) |
| 52-week high | $5.8656 |
| 52-week low | $5.8438 |
| Median price | $5.1776 |
| Average price | $4.8259 |
| Largest weekly change | +9.9% (Feb 18, 2015) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Bayer HealthCare Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Drospirenone and ethinyl estradiol market comparison
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of YAZ 28 TABLET?
The current National Average Drug Acquisition Cost (NADAC) for YAZ 28 TABLET, manufactured by Bayer HealthCare Pharmaceuticals Inc., is $5.8438 per EA (NDC 50419040503), effective Sep 30, 2026.
How has the price of YAZ 28 TABLET changed over time?
Over the history we have for it, the NADAC for YAZ 28 TABLET has risen 114.8%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for YAZ 28 TABLET?
Since Nov 28, 2013, the NADAC for YAZ 28 TABLET has ranged from a low of $2.6654 (Jul 23, 2014) to a high of $5.8909 (Oct 11, 2023), with a median of $5.1776 per EA.
Are there cheaper alternatives to YAZ 28 TABLET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DROSPIRENONE-EE 3-0.02 MG TAB, is $0.1909 per EA — about 97% below YAZ 28 TABLET.
Who manufactures YAZ 28 TABLET?
YAZ 28 TABLET (NDC 50419040503) is labeled by Bayer HealthCare Pharmaceuticals Inc., and CMS classifies it as a brand product.