Product Information

OPZELURA 1.5% CREAM is a brand product labeled by Incyte Corporation, priced at $34.0201 per GM under NDC 50881000705. Its NADAC has been published 210 times since Jun 22, 2022.

OPZELURA 1.5% CREAM

ruxolitinib
$34.0201per GM

Strength

15 mg/g

Manufacturer

Incyte Corporation

NDC

50881000705

Classification

Brand

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

RUXOLITINIB PHOSPHATE

Approval Type

New Drug (NDA)

FDA Application

NDA215309

On Market Since

9/21/2021

Pharmacological Classes

Price Statistics

The NADAC for OPZELURA 1.5% CREAM has been published 210 times since Jun 22, 2022, and over the history we have for it it has risen 8.9%. The table below summarizes its recorded NADAC range and movement.

Current price$34.0201 per GM
All-time high$34.1433 (May 13, 2026)
All-time low$31.2358 (Jun 22, 2022)
52-week high$34.1433
52-week low$33.4719
Median price$32.8296
Average price$32.7616
Largest weekly change+3.0% (Jan 18, 2023)
Weeks tracked210
Tracking sinceJun 22, 2022

Price History

1W

0.0%

1M

-0.0%

3M

-0.4%

6M

+1.6%

1Y

+1.6%

3Y

+5.8%

5Y

N/A

All

+8.9%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the ruxolitinib market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of OPZELURA 1.5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for OPZELURA 1.5% CREAM, manufactured by Incyte Corporation, is $34.0201 per GM (NDC 50881000705), effective Jun 24, 2026.

How has the price of OPZELURA 1.5% CREAM changed over time?

Over the history we have for it, the NADAC for OPZELURA 1.5% CREAM has risen 8.9%. It has been tracked across 210 weekly CMS publications since Jun 22, 2022.

What are the highest and lowest recorded NADAC prices for OPZELURA 1.5% CREAM?

Since Jun 22, 2022, the NADAC for OPZELURA 1.5% CREAM has ranged from a low of $31.2358 (Jun 22, 2022) to a high of $34.1433 (May 13, 2026), with a median of $32.8296 per GM.

Are there cheaper alternatives to OPZELURA 1.5% CREAM?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of OPZELURA 1.5% CREAM, so no direct lower-cost alternative is listed.

Who manufactures OPZELURA 1.5% CREAM?

OPZELURA 1.5% CREAM (NDC 50881000705) is labeled by Incyte Corporation, and CMS classifies it as a brand product.