Product Information

ZOLOFT 25 MG TABLET is a brand product labeled by Viatris Specialty LLC, priced at $14.8792 per EA under NDC 58151057493. Its NADAC has been published 86 times since Jan 1, 2025.

FDA first approved this application on Dec 30, 1991. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the sertraline hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ZOLOFT 25 MG TABLET

sertraline hydrochloride
$14.8792per EA
High Outlier

Strength

25 mg/1

NDC

58151057493

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

1/1/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA019839

FDA Approved

12/30/1991

TE Code

AB

On Market Since

10/30/2024

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for ZOLOFT 25 MG TABLET has been published 86 times since Jan 1, 2025, and over the history we have for it it has risen 6.8%. The table below summarizes its recorded NADAC range and movement.

Current price$14.8792 per EA
All-time high$14.8792 (Aug 19, 2026)
All-time low$13.9253 (Jan 1, 2025)
52-week high$14.8792
52-week low$14.1418
Median price$14.3432
Average price$14.4765
Largest weekly change+5.0% (Jan 7, 2026)
Weeks tracked86
Tracking sinceJan 1, 2025

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+5.2%

3Y

N/A

5Y

N/A

All

+6.8%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 99%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of ZOLOFT 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ZOLOFT 25 MG TABLET, manufactured by Viatris Specialty LLC, is $14.8792 per EA (NDC 58151057493), effective Aug 19, 2026.

How has the price of ZOLOFT 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for ZOLOFT 25 MG TABLET has risen 6.8%. It has been tracked across 86 weekly CMS publications since Jan 1, 2025.

What are the highest and lowest recorded NADAC prices for ZOLOFT 25 MG TABLET?

Since Jan 1, 2025, the NADAC for ZOLOFT 25 MG TABLET has ranged from a low of $13.9253 (Jan 1, 2025) to a high of $14.8792 (Aug 19, 2026), with a median of $14.3432 per EA.

Are there cheaper alternatives to ZOLOFT 25 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SERTRALINE HCL 25 MG TABLET, is $0.0282 per EA — about 99% below ZOLOFT 25 MG TABLET.

Who manufactures ZOLOFT 25 MG TABLET?

ZOLOFT 25 MG TABLET (NDC 58151057493) is labeled by Viatris Specialty LLC, and CMS classifies it as a brand product.