Product Information
ENBREL 25 MG/0.5 ML SYRINGE is a brand product labeled by Immunex Corporation, priced at $2076.2308 per ML under NDC 58406001004. Its NADAC has been published 323 times since Jan 22, 2020.
Strength
25 mg/.5mL
Manufacturer
Immunex CorporationNDC
58406001004
Classification
Brand
Dosage Form
SOLUTION
Route
SUBCUTANEOUS
Last Updated
1/7/2026
Active Ingredients
ETANERCEPTApproval Type
Biologic (BLA)
FDA Application
BLA103795On Market Since
6/7/2019
Pharmacological Classes
Price Statistics
The NADAC for ENBREL 25 MG/0.5 ML SYRINGE has been published 323 times since Jan 22, 2020, and over the history we have for it it has risen 64.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2076.2308 per ML |
|---|---|
| All-time high | $2076.2308 (Jun 24, 2026) |
| All-time low | $1261.8250 (Jan 22, 2020) |
| 52-week high | $2076.2308 |
| 52-week low | $1977.1488 |
| Median price | $1715.6364 |
| Average price | $1689.4837 |
| Largest weekly change | +7.4% (Jan 11, 2023) |
| Weeks tracked | 323 |
| Tracking since | Jan 22, 2020 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the etanercept market page.
Lowest-Cost Alternatives
No alternatives available
Frequently asked questions
What is the NADAC price of ENBREL 25 MG/0.5 ML SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for ENBREL 25 MG/0.5 ML SYRINGE, manufactured by Immunex Corporation, is $2076.2308 per ML (NDC 58406001004), effective Jun 24, 2026.
How has the price of ENBREL 25 MG/0.5 ML SYRINGE changed over time?
Over the history we have for it, the NADAC for ENBREL 25 MG/0.5 ML SYRINGE has risen 64.5%. It has been tracked across 323 weekly CMS publications since Jan 22, 2020.
What are the highest and lowest recorded NADAC prices for ENBREL 25 MG/0.5 ML SYRINGE?
Since Jan 22, 2020, the NADAC for ENBREL 25 MG/0.5 ML SYRINGE has ranged from a low of $1261.8250 (Jan 22, 2020) to a high of $2076.2308 (Jun 24, 2026), with a median of $1715.6364 per ML.
Are there cheaper alternatives to ENBREL 25 MG/0.5 ML SYRINGE?
No other NADAC-published product currently shares the active ingredient, strength, and dosage form of ENBREL 25 MG/0.5 ML SYRINGE, so no direct lower-cost alternative is listed.
Who manufactures ENBREL 25 MG/0.5 ML SYRINGE?
ENBREL 25 MG/0.5 ML SYRINGE (NDC 58406001004) is labeled by Immunex Corporation, and CMS classifies it as a brand product.
Related Drugs
Same classification