Product Information

APTIOM 400 MG TABLET is a brand product labeled by Sumitomo Pharma America, Inc., priced at $44.0400 per EA under NDC 63402020430. Its NADAC has been published 614 times since Nov 19, 2014.

FDA first approved this application on Nov 8, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the ESLICARBAZEPINE ACETATE market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

APTIOM 400 MG TABLET

ESLICARBAZEPINE ACETATE
$44.0400per EA
High Outlier

Strength

400 mg/1

NDC

63402020430

Classification

Brand

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ESLICARBAZEPINE ACETATE

Approval Type

New Drug (NDA)

FDA Application

NDA022416

FDA Approved

11/8/2013

TE Code

AB

On Market Since

4/7/2014

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for APTIOM 400 MG TABLET has been published 614 times since Nov 19, 2014, and over the history we have for it it has risen 138.3%. The table below summarizes its recorded NADAC range and movement.

Current price$44.0400 per EA
All-time high$44.3505 (Jul 15, 2026)
All-time low$18.4811 (Nov 19, 2014)
52-week high$44.3505
52-week low$42.9738
Median price$32.5074
Average price$32.9611
Largest weekly change+9.9% (Jan 10, 2018)
Weeks tracked614
Tracking sinceNov 19, 2014

Price History

1W

-0.1%

1M

-0.1%

3M

-0.3%

6M

-0.7%

1Y

+2.5%

3Y

+14.8%

5Y

+29.5%

All

+138.3%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the ESLICARBAZEPINE ACETATE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of APTIOM 400 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for APTIOM 400 MG TABLET, manufactured by Sumitomo Pharma America, Inc., is $44.0400 per EA (NDC 63402020430), effective Aug 19, 2026.

How has the price of APTIOM 400 MG TABLET changed over time?

Over the history we have for it, the NADAC for APTIOM 400 MG TABLET has risen 138.3%. It has been tracked across 614 weekly CMS publications since Nov 19, 2014.

What are the highest and lowest recorded NADAC prices for APTIOM 400 MG TABLET?

Since Nov 19, 2014, the NADAC for APTIOM 400 MG TABLET has ranged from a low of $18.4811 (Nov 19, 2014) to a high of $44.3505 (Jul 15, 2026), with a median of $32.5074 per EA.

Are there cheaper alternatives to APTIOM 400 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of APTIOM 400 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures APTIOM 400 MG TABLET?

APTIOM 400 MG TABLET (NDC 63402020430) is labeled by Sumitomo Pharma America, Inc., and CMS classifies it as a brand product.