Product Information

HYDROXYZINE HCL 25 MG TABLET is a generic product labeled by McKesson, priced at $0.0346 per EA under NDC 63739048610. Its NADAC has been published 649 times since Nov 28, 2013.

FDA first approved this application on Mar 31, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

HYDROXYZINE HCL 25 MG TABLET

HydrOXYzine Hydrochloride
$0.0346per EA
Discontinued

Strength

25 mg/1

Manufacturer

McKesson

NDC

63739048610

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

4/22/2026

Active Ingredients

HYDROXYZINE DIHYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA040840

FDA Approved

3/31/2008

TE Code

AB

On Market Since

11/11/2009

Pharmacological Classes

Antihistamine
Histamine Receptor Antagonists

Price Statistics

The NADAC for HYDROXYZINE HCL 25 MG TABLET has been published 649 times since Nov 28, 2013, and over the history we have for it it has declined 61.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0346 per EA
All-time high$0.1062 (Apr 15, 2015)
All-time low$0.0341 (Nov 20, 2024)
52-week high$0.0377
52-week low$0.0346
Median price$0.0604
Average price$0.0645
Largest weekly change+60.2% (Jan 19, 2022)
Weeks tracked649
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

-0.4%

1Y

-8.3%

3Y

-27.9%

5Y

-54.9%

All

-61.9%

Last surveyed Apr 29, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 1%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of HYDROXYZINE HCL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROXYZINE HCL 25 MG TABLET, manufactured by McKesson, is $0.0346 per EA (NDC 63739048610), effective Apr 29, 2026.

How has the price of HYDROXYZINE HCL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROXYZINE HCL 25 MG TABLET has declined 61.9%. It has been tracked across 649 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for HYDROXYZINE HCL 25 MG TABLET?

Since Nov 28, 2013, the NADAC for HYDROXYZINE HCL 25 MG TABLET has ranged from a low of $0.0341 (Nov 20, 2024) to a high of $0.1062 (Apr 15, 2015), with a median of $0.0604 per EA.

Are there cheaper alternatives to HYDROXYZINE HCL 25 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROXYZINE HCL 25 MG TABLET, is $0.0342 per EA — about 1% below HYDROXYZINE HCL 25 MG TABLET.

Who manufactures HYDROXYZINE HCL 25 MG TABLET?

HYDROXYZINE HCL 25 MG TABLET (NDC 63739048610) is labeled by McKesson, and CMS classifies it as a generic product.