Product Information

KRISTALOSE 10 GM PACKET is a brand (anda) product labeled by Cumberland Pharmaceuticals Inc., priced at $9.5808 per EA under NDC 66220071930. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Dec 10, 1997. Its Orange Book therapeutic-equivalence code is AA.

KRISTALOSE 10 GM PACKET

lactulose
$9.5808per EA

Strength

10 g/10g

NDC

66220071930

Classification

Brand (ANDA)

Dosage Form

POWDER, FOR SOLUTION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LACTULOSE

Approval Type

Generic (ANDA)

FDA Application

ANDA074712

FDA Approved

12/10/1997

TE Code

AA

On Market Since

1/20/2012

Pharmacological Classes

Acidifying Activity
Osmotic Activity
Osmotic Laxative
Stimulation Large Intestine Fluid/Electrolyte Secretion

Price Statistics

The NADAC for KRISTALOSE 10 GM PACKET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 308.3%. The table below summarizes its recorded NADAC range and movement.

Current price$9.5808 per EA
All-time high$9.6303 (May 13, 2026)
All-time low$2.3468 (Nov 28, 2013)
52-week high$9.6303
52-week low$9.3942
Median price$7.4259
Average price$7.3653
Largest weekly change+137.2% (Jan 22, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+0.0%

1M

+0.0%

3M

+0.0%

6M

-0.5%

1Y

+1.9%

3Y

+19.0%

5Y

+22.9%

All

+308.3%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 15%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of KRISTALOSE 10 GM PACKET?

The current National Average Drug Acquisition Cost (NADAC) for KRISTALOSE 10 GM PACKET, manufactured by Cumberland Pharmaceuticals Inc., is $9.5808 per EA (NDC 66220071930), effective Aug 19, 2026.

How has the price of KRISTALOSE 10 GM PACKET changed over time?

Over the history we have for it, the NADAC for KRISTALOSE 10 GM PACKET has risen 308.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for KRISTALOSE 10 GM PACKET?

Since Nov 28, 2013, the NADAC for KRISTALOSE 10 GM PACKET has ranged from a low of $2.3468 (Nov 28, 2013) to a high of $9.6303 (May 13, 2026), with a median of $7.4259 per EA.

Are there cheaper alternatives to KRISTALOSE 10 GM PACKET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LACTULOSE 10 GM PACKET, is $8.1709 per EA — about 15% below KRISTALOSE 10 GM PACKET.

Who manufactures KRISTALOSE 10 GM PACKET?

KRISTALOSE 10 GM PACKET (NDC 66220071930) is labeled by Cumberland Pharmaceuticals Inc., and CMS classifies it as a brand (anda) product.