Product Information
DUREZOL 0.05% EYE DROPS is a brand product labeled by Sandoz Inc., priced at $42.2491 per ML under NDC 66758008675. Its NADAC has been published 82 times since Jan 29, 2025.
FDA first approved this application on Jun 23, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the difluprednate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
.5 mg/mL
Manufacturer
Sandoz Inc.NDC
66758008675
Classification
Brand
Dosage Form
EMULSION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
DIFLUPREDNATEApproval Type
New Drug (NDA)
FDA Application
NDA022212FDA Approved
6/23/2008
TE Code
AB
On Market Since
1/25/2011
Price Statistics
The NADAC for DUREZOL 0.05% EYE DROPS has been published 82 times since Jan 29, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $42.2491 per ML |
|---|---|
| All-time high | $42.6191 (Dec 10, 2025) |
| All-time low | $42.2491 (Aug 19, 2026) |
| 52-week high | $42.6191 |
| 52-week low | $42.2491 |
| Median price | $42.5462 |
| Average price | $42.4858 |
| Largest weekly change | -0.4% (Dec 17, 2025) |
| Weeks tracked | 82 |
| Tracking since | Jan 29, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the difluprednate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DUREZOL 0.05% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for DUREZOL 0.05% EYE DROPS, manufactured by Sandoz Inc., is $42.2491 per ML (NDC 66758008675), effective Aug 19, 2026.
How has the price of DUREZOL 0.05% EYE DROPS changed over time?
Over the history we have for it, the NADAC for DUREZOL 0.05% EYE DROPS has held within roughly two percent of its current level. It has been tracked across 82 weekly CMS publications since Jan 29, 2025.
What are the highest and lowest recorded NADAC prices for DUREZOL 0.05% EYE DROPS?
Since Jan 29, 2025, the NADAC for DUREZOL 0.05% EYE DROPS has ranged from a low of $42.2491 (Aug 19, 2026) to a high of $42.6191 (Dec 10, 2025), with a median of $42.5462 per ML.
Are there cheaper alternatives to DUREZOL 0.05% EYE DROPS?
No other NADAC-published product currently shares the active ingredient and strength of DUREZOL 0.05% EYE DROPS in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures DUREZOL 0.05% EYE DROPS?
DUREZOL 0.05% EYE DROPS (NDC 66758008675) is labeled by Sandoz Inc., and CMS classifies it as a brand product.