Product Information
FLUTICASONE-SALMETEROL 45-21 is a generic product labeled by Prasco Laboratories, priced at $16.7877 per GM under NDC 66993008696. Its NADAC has been published 149 times since Aug 23, 2023.
Strength
45; 21 ug/1; ug/1
Manufacturer
Prasco LaboratoriesNDC
66993008696
Classification
Generic
Dosage Form
AEROSOL, METERED
Route
RESPIRATORY (INHALATION)
Last Updated
6/17/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021254On Market Since
3/1/2023
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 45-21 has been published 149 times since Aug 23, 2023, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $16.7877 per GM |
|---|---|
| All-time high | $17.0885 (Mar 13, 2024) |
| All-time low | $15.2436 (May 22, 2024) |
| 52-week high | $16.7877 |
| 52-week low | $16.0683 |
| Median price | $16.4135 |
| Average price | $16.3734 |
| Largest weekly change | -7.3% (Apr 17, 2024) |
| Weeks tracked | 149 |
| Tracking since | Aug 23, 2023 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 45-21?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 45-21, manufactured by Prasco Laboratories, is $16.7877 per GM (NDC 66993008696), effective Jun 24, 2026.
How has the price of FLUTICASONE-SALMETEROL 45-21 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 45-21 has held within roughly two percent of its current level. It has been tracked across 149 weekly CMS publications since Aug 23, 2023.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 45-21?
Since Aug 23, 2023, the NADAC for FLUTICASONE-SALMETEROL 45-21 has ranged from a low of $15.2436 (May 22, 2024) to a high of $17.0885 (Mar 13, 2024), with a median of $16.4135 per GM.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 45-21?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as FLUTICASONE-SALMETEROL 45-21, but none are currently priced below it.
Who manufactures FLUTICASONE-SALMETEROL 45-21?
FLUTICASONE-SALMETEROL 45-21 (NDC 66993008696) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.
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Same classification