Product Information
FLUTICASONE-SALMETEROL 45-21 is a generic product labeled by Prasco Laboratories, priced at $16.8534 per GM under NDC 66993008696. Its NADAC has been published 157 times since Aug 23, 2023.
FDA first approved this application on Jun 8, 2006.
Strength
45; 21 ug/1; ug/1
Manufacturer
Prasco LaboratoriesNDC
66993008696
Classification
Generic
Dosage Form
AEROSOL, METERED
Route
RESPIRATORY (INHALATION)
Effective Date
8/19/2026
Active Ingredients
FLUTICASONE PROPIONATE; SALMETEROL XINAFOATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021254FDA Approved
6/8/2006
On Market Since
3/1/2023
Pharmacological Classes
Price Statistics
The NADAC for FLUTICASONE-SALMETEROL 45-21 has been published 157 times since Aug 23, 2023, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $16.8534 per GM |
|---|---|
| All-time high | $17.0885 (Mar 13, 2024) |
| All-time low | $15.2436 (May 22, 2024) |
| 52-week high | $16.9739 |
| 52-week low | $16.1709 |
| Median price | $16.5569 |
| Average price | $16.3997 |
| Largest weekly change | -7.3% (Apr 17, 2024) |
| Weeks tracked | 157 |
| Tracking since | Aug 23, 2023 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of FLUTICASONE-SALMETEROL 45-21?
The current National Average Drug Acquisition Cost (NADAC) for FLUTICASONE-SALMETEROL 45-21, manufactured by Prasco Laboratories, is $16.8534 per GM (NDC 66993008696), effective Aug 19, 2026.
How has the price of FLUTICASONE-SALMETEROL 45-21 changed over time?
Over the history we have for it, the NADAC for FLUTICASONE-SALMETEROL 45-21 has held within roughly two percent of its current level. It has been tracked across 157 weekly CMS publications since Aug 23, 2023.
What are the highest and lowest recorded NADAC prices for FLUTICASONE-SALMETEROL 45-21?
Since Aug 23, 2023, the NADAC for FLUTICASONE-SALMETEROL 45-21 has ranged from a low of $15.2436 (May 22, 2024) to a high of $17.0885 (Mar 13, 2024), with a median of $16.5569 per GM.
Are there cheaper alternatives to FLUTICASONE-SALMETEROL 45-21?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as FLUTICASONE-SALMETEROL 45-21 in a comparable dosage form, but none are currently priced below it.
Who manufactures FLUTICASONE-SALMETEROL 45-21?
FLUTICASONE-SALMETEROL 45-21 (NDC 66993008696) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.