Product Information
LOFEXIDINE 0.18 MG TABLET is a generic product labeled by Prasco Laboratories, priced at $7.8793 per EA under NDC 66993034537. Its NADAC has been published 94 times since Dec 18, 2024.
FDA first approved this application on May 16, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.2 mg/1
Manufacturer
Prasco LaboratoriesNDC
66993034537
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LOFEXIDINE HYDROCHLORIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA209229FDA Approved
5/16/2018
TE Code
AB
On Market Since
8/29/2024
Price Statistics
The NADAC for LOFEXIDINE 0.18 MG TABLET has been published 94 times since Dec 18, 2024, and over the history we have for it it has declined 38.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.8793 per EA |
|---|---|
| All-time high | $12.9814 (Sep 10, 2025) |
| All-time low | $7.8793 (Sep 23, 2026) |
| 52-week high | $12.6568 |
| 52-week low | $7.8793 |
| Median price | $11.4812 |
| Average price | $11.1556 |
| Largest weekly change | -9.3% (Oct 22, 2025) |
| Weeks tracked | 94 |
| Tracking since | Dec 18, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Prasco Laboratories manufacturer profile
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Drug market
lofexidine hydrochloride market comparison
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of LOFEXIDINE 0.18 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LOFEXIDINE 0.18 MG TABLET, manufactured by Prasco Laboratories, is $7.8793 per EA (NDC 66993034537), effective Sep 30, 2026.
How has the price of LOFEXIDINE 0.18 MG TABLET changed over time?
Over the history we have for it, the NADAC for LOFEXIDINE 0.18 MG TABLET has declined 38.8%. It has been tracked across 94 weekly CMS publications since Dec 18, 2024.
What are the highest and lowest recorded NADAC prices for LOFEXIDINE 0.18 MG TABLET?
Since Dec 18, 2024, the NADAC for LOFEXIDINE 0.18 MG TABLET has ranged from a low of $7.8793 (Sep 23, 2026) to a high of $12.9814 (Sep 10, 2025), with a median of $11.4812 per EA.
Are there cheaper alternatives to LOFEXIDINE 0.18 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LOFEXIDINE 0.18 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures LOFEXIDINE 0.18 MG TABLET?
LOFEXIDINE 0.18 MG TABLET (NDC 66993034537) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.