Product Information

VENLAFAXINE HCL ER 225 MG TAB is a generic product labeled by Ascend Laboratories, LLC, priced at $0.4614 per EA under NDC 67877072990. Its NADAC has been published 238 times since Feb 2, 2022.

FDA first approved this application on Jun 10, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

VENLAFAXINE HCL ER 225 MG TAB

Venlafaxine
$0.4614per EA

Strength

225 mg/1

NDC

67877072990

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

VENLAFAXINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA214127

FDA Approved

6/10/2021

TE Code

AB

On Market Since

6/11/2021

Pharmacological Classes

Norepinephrine Uptake Inhibitors
Serotonin Uptake Inhibitors
Serotonin and Norepinephrine Reuptake Inhibitor

Price Statistics

The NADAC for VENLAFAXINE HCL ER 225 MG TAB has been published 238 times since Feb 2, 2022, and over the history we have for it it has declined 87.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4614 per EA
All-time high$3.6016 (Feb 16, 2022)
All-time low$0.4592 (Nov 20, 2024)
52-week high$0.6770
52-week low$0.4614
Median price$0.7400
Average price$1.1005
Largest weekly change+54.1% (Feb 22, 2023)
Weeks tracked238
Tracking sinceFeb 2, 2022

Price History

1W

-7.8%

1M

-7.8%

3M

-12.8%

6M

-7.1%

1Y

-31.8%

3Y

-46.7%

5Y

N/A

All

-87.2%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of VENLAFAXINE HCL ER 225 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for VENLAFAXINE HCL ER 225 MG TAB, manufactured by Ascend Laboratories, LLC, is $0.4614 per EA (NDC 67877072990), effective Aug 19, 2026.

How has the price of VENLAFAXINE HCL ER 225 MG TAB changed over time?

Over the history we have for it, the NADAC for VENLAFAXINE HCL ER 225 MG TAB has declined 87.2%. It has been tracked across 238 weekly CMS publications since Feb 2, 2022.

What are the highest and lowest recorded NADAC prices for VENLAFAXINE HCL ER 225 MG TAB?

Since Feb 2, 2022, the NADAC for VENLAFAXINE HCL ER 225 MG TAB has ranged from a low of $0.4592 (Nov 20, 2024) to a high of $3.6016 (Feb 16, 2022), with a median of $0.7400 per EA.

Are there cheaper alternatives to VENLAFAXINE HCL ER 225 MG TAB?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as VENLAFAXINE HCL ER 225 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures VENLAFAXINE HCL ER 225 MG TAB?

VENLAFAXINE HCL ER 225 MG TAB (NDC 67877072990) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.