Product Information
GLUMETZA ER 1,000 MG TABLET is a brand product labeled by Santarus Inc., priced at $107.1180 per EA under NDC 68012000316. Its NADAC has been published 238 times since Jul 23, 2014.
FDA first approved this application on Jun 3, 2005.
The High Outlier badge above means this manufacturer's average price in the metformin hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
1000 mg/1
Manufacturer
Santarus Inc.NDC
68012000316
Classification
Brand
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
1/22/2025
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA021748FDA Approved
6/3/2005
On Market Since
6/17/2008
Pharmacological Classes
Price Statistics
The NADAC for GLUMETZA ER 1,000 MG TABLET has been published 238 times since Jul 23, 2014, and over the history we have for it it has risen 799.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $107.1180 per EA |
|---|---|
| All-time high | $107.7988 (Jul 13, 2016) |
| All-time low | $11.9136 (Aug 20, 2014) |
| 52-week high | $107.1180 |
| 52-week low | $107.1180 |
| Median price | $107.1180 |
| Average price | $87.0416 |
| Largest weekly change | +500.0% (Jun 24, 2015) |
| Weeks tracked | 238 |
| Tracking since | Jul 23, 2014 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
-0.1%
5Y
-0.1%
All
+799.1%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GLUMETZA ER 1,000 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GLUMETZA ER 1,000 MG TABLET, manufactured by Santarus Inc., is $107.1180 per EA (NDC 68012000316), effective Oct 1, 2025.
How has the price of GLUMETZA ER 1,000 MG TABLET changed over time?
Over the history we have for it, the NADAC for GLUMETZA ER 1,000 MG TABLET has risen 799.1%. It has been tracked across 238 weekly CMS publications since Jul 23, 2014.
What are the highest and lowest recorded NADAC prices for GLUMETZA ER 1,000 MG TABLET?
Since Jul 23, 2014, the NADAC for GLUMETZA ER 1,000 MG TABLET has ranged from a low of $11.9136 (Aug 20, 2014) to a high of $107.7988 (Jul 13, 2016), with a median of $107.1180 per EA.
Are there cheaper alternatives to GLUMETZA ER 1,000 MG TABLET?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 1,000 MG TABLET, is $0.0231 per EA — about 99% below GLUMETZA ER 1,000 MG TABLET.
Who manufactures GLUMETZA ER 1,000 MG TABLET?
GLUMETZA ER 1,000 MG TABLET (NDC 68012000316) is labeled by Santarus Inc., and CMS classifies it as a brand product.