Product Information
DIFLUPREDNATE 0.05% EYE DROP is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $8.9184 per ML under NDC 69238138003. Its NADAC has been published 231 times since Mar 23, 2022.
FDA first approved this application on Nov 17, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/mL
Manufacturer
Amneal Pharmaceuticals NY LLCNDC
69238138003
Classification
Generic
Dosage Form
EMULSION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
DIFLUPREDNATEApproval Type
Generic (ANDA)
FDA Application
ANDA211526FDA Approved
11/17/2021
TE Code
AB
On Market Since
11/18/2021
Price Statistics
The NADAC for DIFLUPREDNATE 0.05% EYE DROP has been published 231 times since Mar 23, 2022, and over the history we have for it it has declined 72.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.9184 per ML |
|---|---|
| All-time high | $31.8469 (Apr 13, 2022) |
| All-time low | $7.0479 (Jun 17, 2026) |
| 52-week high | $11.3753 |
| 52-week low | $7.0479 |
| Median price | $14.3420 |
| Average price | $15.3428 |
| Largest weekly change | +46.0% (Aug 21, 2024) |
| Weeks tracked | 231 |
| Tracking since | Mar 23, 2022 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Difluprednate ophthalmic market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIFLUPREDNATE 0.05% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for DIFLUPREDNATE 0.05% EYE DROP, manufactured by Amneal Pharmaceuticals NY LLC, is $8.9184 per ML (NDC 69238138003), effective Aug 19, 2026.
How has the price of DIFLUPREDNATE 0.05% EYE DROP changed over time?
Over the history we have for it, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has declined 72.0%. It has been tracked across 231 weekly CMS publications since Mar 23, 2022.
What are the highest and lowest recorded NADAC prices for DIFLUPREDNATE 0.05% EYE DROP?
Since Mar 23, 2022, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has ranged from a low of $7.0479 (Jun 17, 2026) to a high of $31.8469 (Apr 13, 2022), with a median of $14.3420 per ML.
Are there cheaper alternatives to DIFLUPREDNATE 0.05% EYE DROP?
No other NADAC-published product currently shares the active ingredient and strength of DIFLUPREDNATE 0.05% EYE DROP in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures DIFLUPREDNATE 0.05% EYE DROP?
DIFLUPREDNATE 0.05% EYE DROP (NDC 69238138003) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.