Product Information

MEMANTINE-DONEPEZIL ER 14-10 MG is a generic product labeled by Vitruvias Therapeutics Inc., priced at $7.3348 per EA under NDC 69680018330. Its NADAC has been published 50 times since Sep 10, 2025.

FDA first approved this application on Jul 15, 2025. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

MEMANTINE-DONEPEZIL ER 14-10 MG

memantine hydrochloride and donepezil hydrochloride
$7.3348per EA

Strength

10; 14 mg/1; mg/1

NDC

69680018330

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA216901

FDA Approved

7/15/2025

TE Code

AB

On Market Since

7/16/2025

Pharmacological Classes

Cholinesterase Inhibitor
Cholinesterase Inhibitors
N-methyl-D-aspartate Receptor Antagonist
NMDA Receptor Antagonists

Price Statistics

The NADAC for MEMANTINE-DONEPEZIL ER 14-10 MG has been published 50 times since Sep 10, 2025, and over the history we have for it it has declined 54.9%. The table below summarizes its recorded NADAC range and movement.

Current price$7.3348 per EA
All-time high$16.2469 (Sep 10, 2025)
All-time low$7.3348 (Aug 19, 2026)
52-week high$16.2469
52-week low$7.3348
Median price$12.8530
Average price$12.6090
Largest weekly change-13.1% (Aug 19, 2026)
Weeks tracked50
Tracking sinceSep 10, 2025

Price History

1W

-13.1%

1M

-13.1%

3M

-27.0%

6M

-42.9%

1Y

N/A

3Y

N/A

5Y

N/A

All

-54.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of MEMANTINE-DONEPEZIL ER 14-10 MG?

The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE-DONEPEZIL ER 14-10 MG, manufactured by Vitruvias Therapeutics Inc., is $7.3348 per EA (NDC 69680018330), effective Aug 19, 2026.

How has the price of MEMANTINE-DONEPEZIL ER 14-10 MG changed over time?

Over the history we have for it, the NADAC for MEMANTINE-DONEPEZIL ER 14-10 MG has declined 54.9%. It has been tracked across 50 weekly CMS publications since Sep 10, 2025.

What are the highest and lowest recorded NADAC prices for MEMANTINE-DONEPEZIL ER 14-10 MG?

Since Sep 10, 2025, the NADAC for MEMANTINE-DONEPEZIL ER 14-10 MG has ranged from a low of $7.3348 (Aug 19, 2026) to a high of $16.2469 (Sep 10, 2025), with a median of $12.8530 per EA.

Are there cheaper alternatives to MEMANTINE-DONEPEZIL ER 14-10 MG?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as MEMANTINE-DONEPEZIL ER 14-10 MG in a comparable dosage form, but none are currently priced below it.

Who manufactures MEMANTINE-DONEPEZIL ER 14-10 MG?

MEMANTINE-DONEPEZIL ER 14-10 MG (NDC 69680018330) is labeled by Vitruvias Therapeutics Inc., and CMS classifies it as a generic product.