Product Information
MEMANTINE-DONEPEZIL ER 28-10 MG is a generic product labeled by Vitruvias Therapeutics Inc., priced at $9.4481 per EA under NDC 69680018530. Its NADAC has been published 50 times since Sep 10, 2025.
FDA first approved this application on Jul 15, 2025. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10; 28 mg/1; mg/1
Manufacturer
Vitruvias Therapeutics Inc.NDC
69680018530
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA216901FDA Approved
7/15/2025
TE Code
AB
On Market Since
7/16/2025
Pharmacological Classes
Price Statistics
The NADAC for MEMANTINE-DONEPEZIL ER 28-10 MG has been published 50 times since Sep 10, 2025, and over the history we have for it it has declined 46.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.4481 per EA |
|---|---|
| All-time high | $17.6769 (Sep 10, 2025) |
| All-time low | $9.4481 (Aug 19, 2026) |
| 52-week high | $17.6769 |
| 52-week low | $9.4481 |
| Median price | $15.1318 |
| Average price | $14.3242 |
| Largest weekly change | -10.5% (Jul 22, 2026) |
| Weeks tracked | 50 |
| Tracking since | Sep 10, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MEMANTINE-DONEPEZIL ER 28-10 MG?
The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE-DONEPEZIL ER 28-10 MG, manufactured by Vitruvias Therapeutics Inc., is $9.4481 per EA (NDC 69680018530), effective Aug 19, 2026.
How has the price of MEMANTINE-DONEPEZIL ER 28-10 MG changed over time?
Over the history we have for it, the NADAC for MEMANTINE-DONEPEZIL ER 28-10 MG has declined 46.6%. It has been tracked across 50 weekly CMS publications since Sep 10, 2025.
What are the highest and lowest recorded NADAC prices for MEMANTINE-DONEPEZIL ER 28-10 MG?
Since Sep 10, 2025, the NADAC for MEMANTINE-DONEPEZIL ER 28-10 MG has ranged from a low of $9.4481 (Aug 19, 2026) to a high of $17.6769 (Sep 10, 2025), with a median of $15.1318 per EA.
Are there cheaper alternatives to MEMANTINE-DONEPEZIL ER 28-10 MG?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as MEMANTINE-DONEPEZIL ER 28-10 MG in a comparable dosage form, but none are currently priced below it.
Who manufactures MEMANTINE-DONEPEZIL ER 28-10 MG?
MEMANTINE-DONEPEZIL ER 28-10 MG (NDC 69680018530) is labeled by Vitruvias Therapeutics Inc., and CMS classifies it as a generic product.