Product Information

SERTRALINE HCL 25 MG TABLET is a generic product labeled by Granules Pharmaceuticals Inc., priced at $0.0282 per EA under NDC 70010020310. Its NADAC has been published 164 times since Jul 5, 2023.

FDA first approved this application on Jan 8, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SERTRALINE HCL 25 MG TABLET

Sertraline hydrochloride
$0.0282per EA

Strength

25 mg/1

NDC

70010020310

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA078403

FDA Approved

1/8/2008

TE Code

AB

On Market Since

5/15/2023

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 25 MG TABLET has been published 164 times since Jul 5, 2023, and over the history we have for it it has declined 32.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0282 per EA
All-time high$0.0417 (Jul 12, 2023)
All-time low$0.0282 (Aug 19, 2026)
52-week high$0.0336
52-week low$0.0282
Median price$0.0326
Average price$0.0333
Largest weekly change-24.8% (Nov 20, 2024)
Weeks tracked164
Tracking sinceJul 5, 2023

Price History

1W

-1.3%

1M

-1.3%

3M

-5.4%

6M

-11.9%

1Y

-14.8%

3Y

-24.9%

5Y

N/A

All

-32.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 25 MG TABLET, manufactured by Granules Pharmaceuticals Inc., is $0.0282 per EA (NDC 70010020310), effective Aug 19, 2026.

How has the price of SERTRALINE HCL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 25 MG TABLET has declined 32.5%. It has been tracked across 164 weekly CMS publications since Jul 5, 2023.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 25 MG TABLET?

Since Jul 5, 2023, the NADAC for SERTRALINE HCL 25 MG TABLET has ranged from a low of $0.0282 (Aug 19, 2026) to a high of $0.0417 (Jul 12, 2023), with a median of $0.0326 per EA.

Are there cheaper alternatives to SERTRALINE HCL 25 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SERTRALINE HCL 25 MG TABLET?

SERTRALINE HCL 25 MG TABLET (NDC 70010020310) is labeled by Granules Pharmaceuticals Inc., and CMS classifies it as a generic product.