Product Information
IBUPROFEN 400 MG TABLET is a generic product labeled by Florida Pharmaceutical Products, LLC, priced at $0.0433 per EA under NDC 71921018050. Its NADAC has been published 184 times since Feb 16, 2022.
FDA first approved this application on Oct 15, 1986. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400 mg/1
Manufacturer
Florida Pharmaceutical Products, LLCNDC
71921018050
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/20/2025
Active Ingredients
IBUPROFENApproval Type
Generic (ANDA)
FDA Application
ANDA071268FDA Approved
10/15/1986
TE Code
AB
On Market Since
10/21/2021
Pharmacological Classes
Price Statistics
The NADAC for IBUPROFEN 400 MG TABLET has been published 184 times since Feb 16, 2022, and over the history we have for it it has declined 9.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0433 per EA |
|---|---|
| All-time high | $0.0543 (Mar 16, 2022) |
| All-time low | $0.0338 (Nov 20, 2024) |
| Median price | $0.0472 |
| Average price | $0.0463 |
| Largest weekly change | -25.2% (Nov 20, 2024) |
| Weeks tracked | 184 |
| Tracking since | Feb 16, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-8.2%
5Y
N/A
All
-9.2%
Last surveyed Aug 20, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 10% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of IBUPROFEN 400 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for IBUPROFEN 400 MG TABLET, manufactured by Florida Pharmaceutical Products, LLC, is $0.0433 per EA (NDC 71921018050), effective Aug 20, 2025.
How has the price of IBUPROFEN 400 MG TABLET changed over time?
Over the history we have for it, the NADAC for IBUPROFEN 400 MG TABLET has declined 9.2%. It has been tracked across 184 weekly CMS publications since Feb 16, 2022.
What are the highest and lowest recorded NADAC prices for IBUPROFEN 400 MG TABLET?
Since Feb 16, 2022, the NADAC for IBUPROFEN 400 MG TABLET has ranged from a low of $0.0338 (Nov 20, 2024) to a high of $0.0543 (Mar 16, 2022), with a median of $0.0472 per EA.
Are there cheaper alternatives to IBUPROFEN 400 MG TABLET?
Yes. 14 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, IBUPROFEN 400 MG TABLET, is $0.0391 per EA — about 10% below IBUPROFEN 400 MG TABLET.
Who manufactures IBUPROFEN 400 MG TABLET?
IBUPROFEN 400 MG TABLET (NDC 71921018050) is labeled by Florida Pharmaceutical Products, LLC, and CMS classifies it as a generic product.