Product Information
GUANFACINE HCL ER 3 MG TABLET is a generic product labeled by Advagen Pharma Ltd., priced at $0.1658 per EA under NDC 72888022601. Its NADAC has been published 41 times since Dec 24, 2025.
FDA first approved this application on Apr 15, 2025. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
3 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888022601
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA219689FDA Approved
4/15/2025
TE Code
AB
On Market Since
4/15/2025
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE HCL ER 3 MG TABLET has been published 41 times since Dec 24, 2025, and over the history we have for it it has declined 16.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1658 per EA |
|---|---|
| All-time high | $0.2020 (Feb 11, 2026) |
| All-time low | $0.1636 (Jul 22, 2026) |
| 52-week high | $0.2020 |
| 52-week low | $0.1636 |
| Median price | $0.1764 |
| Average price | $0.1788 |
| Largest weekly change | -6.2% (Mar 18, 2026) |
| Weeks tracked | 41 |
| Tracking since | Dec 24, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Advagen Pharma Ltd. manufacturer profile
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Drug market
GUANFACINE market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUANFACINE HCL ER 3 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE HCL ER 3 MG TABLET, manufactured by Advagen Pharma Ltd., is $0.1658 per EA (NDC 72888022601), effective Sep 30, 2026.
How has the price of GUANFACINE HCL ER 3 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE HCL ER 3 MG TABLET has declined 16.4%. It has been tracked across 41 weekly CMS publications since Dec 24, 2025.
What are the highest and lowest recorded NADAC prices for GUANFACINE HCL ER 3 MG TABLET?
Since Dec 24, 2025, the NADAC for GUANFACINE HCL ER 3 MG TABLET has ranged from a low of $0.1636 (Jul 22, 2026) to a high of $0.2020 (Feb 11, 2026), with a median of $0.1764 per EA.
Are there cheaper alternatives to GUANFACINE HCL ER 3 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as GUANFACINE HCL ER 3 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures GUANFACINE HCL ER 3 MG TABLET?
GUANFACINE HCL ER 3 MG TABLET (NDC 72888022601) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.