Product Information

TYRVAYA 0.03 MG NASAL SPRAY is a brand product labeled by Oyster Point Pharma, Inc., priced at $79.6369 per ML under NDC 73521003002. Its NADAC has been published 202 times since Aug 17, 2022.

The High Outlier badge above means this manufacturer's average price in the varenicline market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

TYRVAYA 0.03 MG NASAL SPRAY

varenicline
$79.6369per ML
High Outlier

Strength

.03 mg/.05mL

NDC

73521003002

Classification

Brand

Dosage Form

SPRAY

Route

NASAL

Last Updated

6/17/2026

Active Ingredients

VARENICLINE TARTRATE

Approval Type

New Drug (NDA)

FDA Application

NDA213978

On Market Since

10/20/2021

Pharmacological Classes

Cholinergic Agonists
Cholinergic Receptor Agonist
Partial Cholinergic Nicotinic Agonist
Partial Cholinergic Nicotinic Agonists

Price Statistics

The NADAC for TYRVAYA 0.03 MG NASAL SPRAY has been published 202 times since Aug 17, 2022, and over the history we have for it it has risen 17.6%. The table below summarizes its recorded NADAC range and movement.

Current price$79.6369 per ML
All-time high$79.6428 (Jun 10, 2026)
All-time low$67.7413 (Aug 17, 2022)
52-week high$79.6428
52-week low$77.9486
Median price$76.1686
Average price$75.2045
Largest weekly change+7.0% (Jan 18, 2023)
Weeks tracked202
Tracking sinceAug 17, 2022

Price History

1W

0.0%

1M

-0.0%

3M

+0.1%

6M

+2.1%

1Y

+2.1%

3Y

+9.9%

5Y

N/A

All

+17.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the varenicline market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of TYRVAYA 0.03 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for TYRVAYA 0.03 MG NASAL SPRAY, manufactured by Oyster Point Pharma, Inc., is $79.6369 per ML (NDC 73521003002), effective Jun 24, 2026.

How has the price of TYRVAYA 0.03 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for TYRVAYA 0.03 MG NASAL SPRAY has risen 17.6%. It has been tracked across 202 weekly CMS publications since Aug 17, 2022.

What are the highest and lowest recorded NADAC prices for TYRVAYA 0.03 MG NASAL SPRAY?

Since Aug 17, 2022, the NADAC for TYRVAYA 0.03 MG NASAL SPRAY has ranged from a low of $67.7413 (Aug 17, 2022) to a high of $79.6428 (Jun 10, 2026), with a median of $76.1686 per ML.

Are there cheaper alternatives to TYRVAYA 0.03 MG NASAL SPRAY?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of TYRVAYA 0.03 MG NASAL SPRAY, so no direct lower-cost alternative is listed.

Who manufactures TYRVAYA 0.03 MG NASAL SPRAY?

TYRVAYA 0.03 MG NASAL SPRAY (NDC 73521003002) is labeled by Oyster Point Pharma, Inc., and CMS classifies it as a brand product.