Product Information
TYRVAYA 0.03 MG NASAL SPRAY is a brand product labeled by Oyster Point Pharma, Inc., priced at $79.5996 per ML under NDC 73521003002. Its NADAC has been published 210 times since Aug 17, 2022.
FDA first approved this application on Oct 15, 2021.
The High Outlier badge above means this manufacturer's average price in the varenicline market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
.03 mg/.05mL
Manufacturer
Oyster Point Pharma, Inc.NDC
73521003002
Classification
Brand
Dosage Form
SPRAY
Route
NASAL
Effective Date
8/19/2026
Active Ingredients
VARENICLINE TARTRATEApproval Type
New Drug (NDA)
FDA Application
NDA213978FDA Approved
10/15/2021
On Market Since
10/20/2021
Pharmacological Classes
Price Statistics
The NADAC for TYRVAYA 0.03 MG NASAL SPRAY has been published 210 times since Aug 17, 2022, and over the history we have for it it has risen 17.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $79.5996 per ML |
|---|---|
| All-time high | $79.6428 (Jun 10, 2026) |
| All-time low | $67.7413 (Aug 17, 2022) |
| 52-week high | $79.6428 |
| 52-week low | $77.9942 |
| Median price | $76.1686 |
| Average price | $75.3725 |
| Largest weekly change | +7.0% (Jan 18, 2023) |
| Weeks tracked | 210 |
| Tracking since | Aug 17, 2022 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the varenicline market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TYRVAYA 0.03 MG NASAL SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for TYRVAYA 0.03 MG NASAL SPRAY, manufactured by Oyster Point Pharma, Inc., is $79.5996 per ML (NDC 73521003002), effective Aug 19, 2026.
How has the price of TYRVAYA 0.03 MG NASAL SPRAY changed over time?
Over the history we have for it, the NADAC for TYRVAYA 0.03 MG NASAL SPRAY has risen 17.5%. It has been tracked across 210 weekly CMS publications since Aug 17, 2022.
What are the highest and lowest recorded NADAC prices for TYRVAYA 0.03 MG NASAL SPRAY?
Since Aug 17, 2022, the NADAC for TYRVAYA 0.03 MG NASAL SPRAY has ranged from a low of $67.7413 (Aug 17, 2022) to a high of $79.6428 (Jun 10, 2026), with a median of $76.1686 per ML.
Are there cheaper alternatives to TYRVAYA 0.03 MG NASAL SPRAY?
No other NADAC-published product currently shares the active ingredient and strength of TYRVAYA 0.03 MG NASAL SPRAY in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TYRVAYA 0.03 MG NASAL SPRAY?
TYRVAYA 0.03 MG NASAL SPRAY (NDC 73521003002) is labeled by Oyster Point Pharma, Inc., and CMS classifies it as a brand product.